Infinite Loops

Every Thursday, join Jim O'Shaughnessy and his favorite people as they arm you with the tools & fresh perspectives required to upgrade your HumanOS and thrive in our messy, probabilistic world. Visit our Substack at newsletter.osv.llc for full transcripts, highlights, weekly doses of timeless wisdom, and a bounty of other goodies designed to make you go, "Hmm that's interesting!"

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Every guest on Infinite Loops

269 guests, ranked by how many people never want them back.

1. —
   Eric Stubin
   0 votes

   Never again
2. —
   Frederik Gieschen

   Frederik Gieschen — On Agility, Agreeableness, Alchemy & the Arena · 2 episodes

   0 votes

   Never again
3. —
   Gabriel Kennedy

   Gabriel Kennedy — The Life and Thought Crimes of Robert Anton Wilson (EP.258) · Mar 2025

   0 votes

   Never again
4. —
   Gena Gorlin

   Dr. Gena Gorlin — How to Build a Builder (EP.236) · Oct 2024

   0 votes

   Never again
5. —
   Grant Mitchell

   Grant Mitchell — The Potential of AI Drug Repurposing · May 2024

   0 votes

   Never again
6. —
   Herbert Lui

   Herbert Lui — Creative Doing (EP.129) · Oct 2022

   0 votes

   Never again
7. —
   Israel Balogun
   0 votes

   Never again
8. —
   Jake Taylor

   Jake Taylor — Getting Better at Decision Making (EP.96) · Mar 2022

   0 votes

   Never again
9. —
   Jameson Olsen

   Jameson Olsen - Becoming the Main Character (Ep. 322) · Jul 2026

   0 votes

   Never again
10. —
    Jason Carman

    Jason Carman — Filmmaking at the Frontier (EP.260) · Mar 2025

    0 votes

    Never again
11. —
    Jay Reno

    Jay Reno — Making A Point (EP.247) · Dec 2024

    0 votes

    Never again
12. —
    Jay Sanguinetti

    Jay Sanguinetti — Neuro Technologies to Enhance Cognition (EP.79) · Dec 2021

    0 votes

    Never again
13. —
    Jay Yang

    Jay Yang — The Power of Permissionless Action (EP. 286) · Oct 2025

    0 votes

    Never again
14. —
    Jean-Marc Daecius

    Jean-Marc Daecius - The Last Human Chief of Staff (Ep. 300) · Feb 2026

    0 votes

    Never again
15. —
    John Sills

    John Sills — The Human Experience (EP.159) · May 2023

    0 votes

    Never again
16. —
    Johnny Nelson

    Johnny Nelson — Past, Present, and Future of Social Media (EP.58) · Jul 2021

    0 votes

    Never again
17. —
    Julia Sonnevend

    Julia Sonnevend — Charming! (EP.230) · Aug 2024

    0 votes

    Never again
18. —
    Julian Gough

    Julian Gough — The Egg and The Rock (Infinite Loops Classics) · 2 episodes

    0 votes

    Never again
19. —
    Julie Fredrickson

    Julie Fredrickson - The Right to Compute: AI Agents, Nuclear Power & Human Data (Ep. 330) · 2 episodes

    0 votes

    Never again
20. —
    Lawrence Yeo

    Lawrence Yeo — The Inner Compass (EP.275) · Jul 2025

    0 votes

    Never again
21. —
    Liberty RPF

    Liberty RPF — On Creation and Curation (EP.134) · Nov 2022

    0 votes

    Never again
22. —
    Linda Lebrun

    Linda Lebrun — The Substack Economy (EP.59) · Aug 2021

    0 votes

    Never again
23. —
    Liz Hall

    Liz Hall - An Outsider's Perspective (EP.04) · Mar 2020

    0 votes

    Never again
24. —
    Liz Wallenstein

    Liz Wallenstein + Dr Michael Donnino — The Mind-Body Connection (EP.126) · Oct 2022

    0 votes

    Never again
25. —
    Logan Chipkin
    0 votes

    Never again
26. —
    Luis Seco

    Luis Seco — On Mathematical Beethovens, Decentralized Education & the Voyage to the Human Brain (EP.243) · Nov 2024

    0 votes

    Never again
27. —
    Luke Fehily

    Luke Fehily — Ireland's Innovation Playbook (EP.256) · Feb 2025

    0 votes

    Never again
28. —
    Madelaine D'Angelo

    Madelaine D'Angelo - Quantifying the Art Market (EP.03) · Mar 2020

    0 votes

    Never again
29. —
    Marc Dennis

    Marc Dennis — Painting the Punchline (EP.293) · Dec 2025

    0 votes

    Never again
30. —
    Marisa Adler
    0 votes

    Never again
31. —
    Mark Daniel

    Mark Daniel — How to Find a Kaleidoscopic Alien (EP.254) · Feb 2025

    0 votes

    Never again
32. —
    Martha Sharpe

    Nat & Martha Sharpe — The Conflict between Agency & Community (EP.163) · May 2023

    0 votes

    Never again
33. —
    Massimo Marinelli

    Massimo Marinelli — Premier League Economics & Sports Investing (EP.60) · Aug 2021

    0 votes

    Never again
34. —
    Max Arbitrage

    Max Arbitrage — Technological Advancements in Healthcare (EP.71) · 2 episodes

    0 votes

    Never again
35. —
    Max Meyer

    Max Meyer Launched a Print Magazine in 2024. Here's Why. (EP.245) · Dec 2024

    0 votes

    Never again
36. —
    Michael Breitenbach

    Michael Breitenbach — On Crypto, AI & Cynicism (EP.150) · Mar 2023

    0 votes

    Never again
37. —
    Michael Donnino
    0 votes

    Never again
38. —
    Michael Perry

    Michael Perry — Improbable Mentors and the Art of Midwestern Storytelling (EP. 289) · Nov 2025

    0 votes

    Never again
39. —
    Michael S. Falk

    Michael S. Falk — A Passionate Advocate For Economic Growth (EP.49) · May 2021

    0 votes

    Never again
40. —
    Michael Strong

    Michael Strong — Let's Get Socratical (EP.252) · Jan 2025

    0 votes

    Never again