Into the Impossible With Brian Keating

Think like a physicist. Wonder like a human. Into the Impossible is where Cosmic Conversations happen — uniting Nobel Prize winners, iconoclasts, authors, and technologists to explore reality’s deepest questions. From AI to aliens, from biophysics to the brain, from the cosmos to the multiverse, Brian Keating, Chancellor’s Distinguished Professor of Physics at UC San Diego covers it all. If you’ve ever asked What’s out there? or What’s next?, this is where curiosity meets clarity. Learn to think like this. 🎙 Full episodes, notes & more: briankeating.com/podcast

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Every guest on Into the Impossible With Brian Keating

334 guests, ranked by how many people never want them back.

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George Church
Will this NEW Scientific Breakthrough Make Us Immune to Everything? George Church - #524 · Oct 2025

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John Mather
Q&A with John Mather on the James Webb Space Telescope (#382) · 3 episodes

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Julian Dorey
What Really Happened In Antarctica? Julian Dorey x Brian Keating · Dec 2025

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Kevin Knuth
Dead Cows, Aliens, & Ghosts: How Kevin Knuth Connects Them All · Jun 2026

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Moiya McTier
The Milky Way: An Autobiography with Dr. Moiya McTier (#250) · 2 episodes

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Stuart Hameroff
Stuart Hameroff: Is the Human Brain a Quantum Computer? (#353) · Oct 2023

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Chris Hadfield
Chris Hadfield’s Final Orbit! The Moon Landing Hoax, UAPs, China & the New Space Race - #522 · 2 episodes

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Delilah Gates
Delilah Gates: Black Hole Basics! (#156) · Jun 2021

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Eugenia Cheng
Category Theory: Exploring Mathematics’ Deepest Truths With Eugenia Cheng (#362) · Oct 2023

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Hakeem Oluseyi
The Universe Is Trying to Destroy All Matter. Hakeem Oluseyi - #552 · 4 episodes

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John Eric Goff
The Physics of Krav Maga with author and physics Professor John Eric Goff (#037) · Apr 2020

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John Martinis
John Martinis: The Nobel Physicist Behind Macroscopic Quantum Tunneling - #566 · Aug 2026

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Katherine Freese
EXCLUSIVE: Katherine Freese Has Evidence of Dark Stars! (#365) · Nov 2023

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Lisa Kaltenegger
Searching for Alien Earths with Lisa Kaltenegger [Ep. 411] · 2 episodes

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Matt Kaplan
The Doctor Everyone Mocked — Until His 'Crazy' Theory Wiped Out a Killer Disease. Matt Kaplan - #547 · 2 episodes

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Sarah Scoles
Aliens are NOT here! With Sarah Scoles (#295) · 2 episodes

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Seth Shostak
Confessions of an Alien Hunter with Seth Shostak (2021) · 2 episodes

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Stephon Alexander
Stephon Alexander: Fear of a Black Universe (#179) · 2 episodes

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Wendy Freedman
Did JWST Just Solve the Biggest Crisis in Cosmology? Wendy Freedman [Ep. 461] · Oct 2024

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Allison Schrager
Allison Schrager: Brothel Economics And Other Unexpected Places to Understand Risk (#128) · Mar 2021

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Charles Seife
Laser Fusion: Is it Hype? Professor Charles Seife (#283) · 2 episodes

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Chris Lintott
Accidental Discoveries That Shaped Astronomy | Chris Lintott · Jul 2024

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Dan Green
Dan Green Physics is NOT In Crisis! (#296) · Feb 2023

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Evan Carmichael
Evan Carmichael: What Is Your One Word? (#095) · Nov 2020

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Brian Schmidt
Brian Schmidt:Nobel Prizewinner: Cosmic Acceleration and Collaboration (#201) · Dec 2021

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David Pogue
David Pogue: How to Prepare for Climate Change! (#140) · Apr 2021

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Donna Strickland
Nobel Laureate Donna Strickland: Experimental Physics Is Fun! (#380) · Dec 2023

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Felix Flicker
Felix Flicker: The Magic of Physics on The Into The Impossible Podcast (#318) · May 2023

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Frank Close
The Elusive Higgs Boson: Frank Close (#238) · Jul 2022

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Rebecca Boyle
How Our Moon Shaped the Course of Human History and Humankind w/ Rebecca Boyle (#404) · Apr 2024

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Suzie Sheehy
What’s the Matter of Everything? Particle Physicist Suzie Sheehy on the INTO THE IMPOSSIBLE Podcast (#300) · Feb 2023

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Marcus Chown
How Black Holes Break Reality | Marcus Chown [Ep. 493] · May 2025

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Vivienne Ming
This AI Broke Every Benchmark — Then It Did Something Worse. Vivienne Ming - #551 · Apr 2026

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Andrei Linde
“I only had 30 minutes to Invent Eternal Inflation!” Andrei Linde | INTO THE IMPOSSIBLE Podcast (#310) · Apr 2023

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Cory Klippsten
Cory Klippsten (SwanBitcoin.com) The Case AGAINST Bitcoin EXPLAINED! (#125) · Mar 2021

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Jim Simons
Jim Simons: Life Lessons from the ‘World’s Smartest Billionaire’ (#054) · Jun 2020

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Katalin Karikó
The mRNA Breakthrough That Changed Medicine Forever with Nobel Laureate Katalin Karikó [Ep. 464] · Nov 2024

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Michael Turner
Michael Turner Explains the Origins and Mysteries of Dark Energy (#367) · Nov 2023

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Sheldon Glashow
Sheldon Glashow: The Power of Useless Ideas! (#099) · Dec 2020

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Tim Palmer
Chaos, Covid, & Climate Change with Professor Tim Palmer (#267) · Oct 2022

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