Into the Impossible With Brian Keating

Think like a physicist. Wonder like a human. Into the Impossible is where Cosmic Conversations happen — uniting Nobel Prize winners, iconoclasts, authors, and technologists to explore reality’s deepest questions. From AI to aliens, from biophysics to the brain, from the cosmos to the multiverse, Brian Keating, Chancellor’s Distinguished Professor of Physics at UC San Diego covers it all. If you’ve ever asked What’s out there? or What’s next?, this is where curiosity meets clarity. Learn to think like this. 🎙 Full episodes, notes & more: briankeating.com/podcast

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Every guest on Into the Impossible With Brian Keating

334 guests, ranked by how many people never want them back.

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Steve McCloskey
UC San Diego Alumnus, Nanome.ai Co-Founder & CEO Steve McCloskey interviewed by Stuart Volkow (#031) · Dec 2019

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Stuart Volkow

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Tevin Naidu
What’s the Relationship Between Matter and Space-Time? w/ Tevin Naidu · Jun 2024

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Thomas Cech
Life's Catalyst: RNA with Thomas Cech [Ep. 423] · Jun 2024

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UCSB Professor Ben Mazin
The Joy of Ex-perimental Astrophysics with UCSB Professor Ben Mazin (#172) · Aug 2021

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Unni Turrettini
Unni Turrettini: Betraying the Nobel: Secrets, Corruption, and the World’s Most Prestigious Prize (#087) · Nov 2020

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Will Kinney
What Happened Before the Big Bang? | An Infinity of Worlds - Will Kinney (#224) · Apr 2022

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Arthur Brooks
The PHYSICS Of Happiness - Arthur C Brooks - #509 · Aug 2025

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John Lennox
Has AI Become God? The Ultimate THREAT of Artificial Intelligence. John C. Lennox - #540 · Feb 2026

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J Craig Venter
Engineering Synthetic Life With Craig Venter (#385) · Jan 2024

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Heather Mac Donald
Heather Lynn Mac Donald: A Classic Modern University (#067) · Aug 2020

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Louis Ignarro
From Pipe Bombs to Viagra: Nobel Prize Winner’s Secrets Revealed - Lou Ignarro - #521 · Oct 2025

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Terence Tao
Can AI help us solve the hardest problems in Mathematics? Terry Tao - #535 · 2 episodes

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Rebecca Newberger Goldstein
Genius Philosopher: The Law of Physics That Explains Why Your Life Falls Apart. Rebecca Goldstein - #549 · Apr 2026

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