Latent Space: The AI Engineer Podcast
The podcast by and for AI Engineers! In 2025, over 10 million readers and listeners came to Latent Space to hear about news, papers and interviews in Software 3.0. We cover Foundation Models changing every domain in Code Generation, Multimodality, AI Agents, GPU Infra and more, directly from the founders, builders, and thinkers involved in pushing the cutting edge. Striving to give you both the definitive take on the Current Thing down to the first introduction to the tech you'll be using in the next 3 months! We break news and exclusive interviews from OpenAI, Anthropic, Gemini, Meta (Soumith Chintala), Sierra (Bret Taylor), tiny (George Hotz), Databricks/MosaicML (Jon Frankle), Modular (Chris Lattner), Answer.ai (Jeremy Howard), et al. Full show notes always on https://latent.space Sponsorship and business inquiries: business@latent.space www.latent.space
WebsiteEvery guest on Latent Space: The AI Engineer Podcast
202 guests, ranked by how many people never want them back.
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Michael Royzen
Beating GPT-4 with Open Source LLMs — with Michael Royzen of Phind · Nov 2023
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Michelle Pokrass
From API to AGI: Structured Outputs, OpenAI API platform and O1 Q&A — with Michelle Pokrass & OpenAI Devrel + Strawberry team · Sep 2024
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Mike Conover
How AI is eating Finance — with Mike Conover of Brightwave · 2 episodes
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Mikhail Parakhin
Shopify’s AI Phase Transition: 2026 Usage Explosion, Unlimited Opus-4.6 Token Budget, Tangle, Tangent, SimGym — with Mikhail Parakhin, Shopify CTO · Apr 2026
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Myra Deng
The First Mechanistic Interpretability Frontier Lab — Myra Deng & Mark Bissell of Goodfire AI · Feb 2026
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Nader Khalil
NVIDIA's AI Engineers: Agent Inference at Planetary Scale and "Speed of Light" — Nader Khalil (Brev), Kyle Kranen (Dynamo) · Mar 2026
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Pavan Kumar Reddy
Mistral: Voxtral TTS, Forge, Leanstral, & what's next for Mistral 4 — w/ Pavan Kumar Reddy & Guillaume Lample · Mar 2026
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Philip Kiely
The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten · Aug 2026
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Reza Shabani
Training a SOTA Code LLM in 1 week and Quantifying the Vibes — with Reza Shabani of Replit · May 2023
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Ron Alfa
🔬 Training Transformers to solve 95% failure rate of Cancer Trials — Ron Alfa & Daniel Bear, Noetik · Apr 2026
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Rune Kvist
Underwriting Superintelligence: Backing Agents you can Sue — Rune Kvist, AIUC · Sep 2026
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Ryan Lopopolo
Extreme Harness Engineering for Token Billionaires: 1M LOC, 1B toks/day, 0% human code, 0% human review — Ryan Lopopolo, OpenAI Frontier & Symphony · Apr 2026
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Samuel Colvin
Agent Engineering with Pydantic + Graphs — with Samuel Colvin · Feb 2025
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Sarah Catanzaro
[State of AI Startups] Memory/Learning, RL Envs & DBT-Fivetran — Sarah Catanzaro, Amplify · Dec 2025
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Sarah Nagy
From Astrophysics to AI: Building the future AI Data Stack — with Sarah Nagy of Seek.ai · Mar 2023
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Sharif Shameem
The AI Founder Gene: Being Early, Building Fast, and Believing in Greatness — with Sharif Shameem of Lexica · May 2023
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Solomon Hykes
[AIEWF Preview] Containing Agent Chaos — Solomon Hykes · Jun 2025
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Soumith Chintala
Open Source AI is AI we can Trust — with Soumith Chintala of Meta AI · Mar 2024
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Tianqi Chen
LLMs Everywhere: Running 70B models in browsers and iPhones using MLC — with Tianqi Chen of CMU / OctoML · Aug 2023
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Tri Dao
FlashAttention 2: making Transformers 800% faster w/o approximation - with Tri Dao of Together AI · Jul 2023
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Walden Yan
The Age of Async Agents — Cognition's Walden Yan & OpenInspect's Cole Murray · May 2026
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William Beauchamp
Outlasting Noam Shazeer, crowdsourcing Chai AI with >1.4m DAU, and becoming the "Western DeepSeek" — with William Beauchamp, Chai Research · Jan 2025
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Wing Lian
The Busy Person's Intro to Finetuning & Open Source AI - Wing Lian, Axolotl · Dec 2023
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Yaroslav Azhnyuk
The Autonomous Drone Tech Stack & Economics of Drones — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion · May 2026
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Recent episodes
223 episodes from the feed, newest first.
- Sep 2026
- Sep 2026
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🔬“We have foundation models for language, not for physics” — Anima Anandkumar, Bren Professor of ComputingAug 2026
with Anima Anandkumar
- Aug 2026
- Aug 2026
- Aug 2026
- Jul 2026
- Jul 2026
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🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)Jul 2026
with Bo Wang
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🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila SciencesJul 2026
with Andy Beam
- Jul 2026
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🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AIJul 2026
with Evan Feinberg
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Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, DatabricksJun 2026
with Matei Zaharia
- Jun 2026
- Jun 2026
- Jun 2026
- Jun 2026
- Jun 2026
- Jun 2026
- Jun 2026
- Jun 2026
- May 2026
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