Literally! With Rob Lowe

This is literally a podcast where people I love, admire, and know well will be in a safe space to really let their hair down (assuming they have any). I will cover the thoughtful to the extremely random. So join me and my guests from the world of movies, TV, sports, music, and culture for fun, wide-ranging, free-wheeling conversations. Subscribe to SiriusXM Podcasts+ to listen to new episodes of Literally with Rob Lowe ad-free. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

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Every guest on Literally! With Rob Lowe

262 guests, ranked by how many people never want them back.

1. —
   Patton Oswalt

   Patton Oswalt: For the Love of It · Sep 2021

   0 votes

   Never again
2. —
   Vanessa Bayer

   Vanessa Bayer: It's More Fun With Cookies (Re-Release) · 2 episodes

   0 votes

   Never again
3. —
   Lindsey Buckingham

   Lindsey Buckingham: It Keeps Evolving · Nov 2021

   0 votes

   Never again
4. —
   Ellen Burstyn

   Ellen Burstyn: Stop Acting · Apr 2026

   0 votes

   Never again
5. —
   Danny Elfman

   Danny Elfman: The Chili Pepper Thing · Oct 2021

   0 votes

   Never again
6. —
   Katey Sagal

   Katey Sagal: Berry Pie · Apr 2024

   0 votes

   Never again
7. —
   Laraine Newman

   Laraine Newman: The Shame of the Senso-Rings (Re-Release) · 2 episodes

   0 votes

   Never again
8. —
   George Lopez

   George Lopez: You Should Stay On TV · Jan 2021

   0 votes

   Never again
9. —
   Ben Schwartz

   Ben Schwartz: Human Jack in the Box · Apr 2022

   0 votes

   Never again
10. —
    Terry Crews

    Terry Crews: A King in His Kingdom · Jun 2026

    0 votes

    Never again
11. —
    Nathan Lane

    Nathan Lane: The Stars Align · Jul 2022

    0 votes

    Never again
12. —
    Aaron Sorkin

    Aaron Sorkin: Well There You Have It (Re-Release) · 2 episodes

    0 votes

    Never again
13. —
    Howie Mandel

    Howie Mandel: Count Chocula · Jul 2025

    0 votes

    Never again
14. —
    Seth MacFarlane

    Seth MacFarlane: Over My Skis · Jun 2022

    0 votes

    Never again
15. —
    Topher Grace

    Topher Grace: Wrap it up Counselor · Mar 2022

    0 votes

    Never again
16. —
    Michael Douglas

    Michael Douglas: Taking the Makeup Off · Apr 2022

    0 votes

    Never again
17. —
    Busy Philipps

    Busy Philipps: The Right Time · Jul 2022

    0 votes

    Never again
18. —
    Jo Koy

    Jo Koy: In The Clutch · Nov 2020

    0 votes

    Never again
19. —
    Rob Riggle

    Rob Riggle: It'll Break Ya! · Feb 2023

    0 votes

    Never again
20. —
    Iliza Shlesinger

    Iliza Shlesinger: Ty Cobb Salad · Jul 2021

    0 votes

    Never again
21. —
    Jason Alexander

    Jason Alexander: Bat Mitzvah Limousine · Jun 2021

    0 votes

    Never again
22. —
    Sebastian Maniscalco

    Sebastian Maniscalco: Kids These Days · 2 episodes

    0 votes

    Never again
23. —
    Fortune Feimster

    Fortune Feimster: Oktoberfest with Arnold · Apr 2025

    0 votes

    Never again
24. —
    Jeff Ross

    Jeff Ross: Judgmental Yoga · Mar 2022

    0 votes

    Never again
25. —
    Kevin Nealon

    Kevin Nealon: Huffing Onions · 2 episodes

    0 votes

    Never again
26. —
    Casey Affleck

    Casey Affleck: Life in the Slow Lane · Aug 2024

    0 votes

    Never again
27. —
    David Crosby

    David Crosby: Cosmic Hippie · Dec 2021

    0 votes

    Never again
28. —
    Katie Couric

    Katie Couric: The Prompter is Off (Re-Release) · 2 episodes

    0 votes

    Never again
29. —
    Eric Andre

    Eric Andre: Quit If You Can · Nov 2020

    0 votes

    Never again
30. —
    Jane Lynch

    Jane Lynch: Stalking Tony The Tiger (Re-Release) · 2 episodes

    0 votes

    Never again
31. —
    Natasha Leggero

    Natasha Leggero: Anything for the Laugh · Apr 2023

    0 votes

    Never again
32. —
    Brian Grazer

    Brian Grazer: Energy Oriented · Jan 2024

    0 votes

    Never again
33. —
    Gabriel Iglesias

    Gabriel Iglesias: The Merch Master (Re-Release) · 2 episodes

    0 votes

    Never again
34. —
    Josh Groban

    Josh Groban: A Beard Is Contour for Men · May 2026

    0 votes

    Never again
35. —
    Nick Offerman

    Nick Offerman: The Ted Experience · Aug 2020

    0 votes

    Never again
36. —
    Robert Downey Jr

    Robert Downey Jr: History Class (Re-Release) · 2 episodes

    0 votes

    Never again
37. —
    Alicia Silverstone

    Alicia Silverstone: Irish Slang · Sep 2025

    0 votes

    Never again
38. —
    Shaquille O'Neal

    Shaquille "Shaq" O'Neal: A Night at the Roxbury · Nov 2025

    0 votes

    Never again
39. —
    James Marsden

    James Marsden: The Chiseler · Jun 2023

    0 votes

    Never again
40. —
    Keegan-Michael Key

    Keegan Michael-Key: Shrimpshramp Reduction (Re-Release) · 2 episodes

    0 votes

    Never again