The a16z Show

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

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Every guest on The a16z Show

694 guests, ranked by how many people never want them back.

1. —
   Antoine Martin
   0 votes

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2. —
   Anurupa Ganguly

   Fixing Education in America: What's Stopping Us? · Dec 2024

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3. —
   Ara Kharazian

   Why AI Isn’t Killing SaaS Yet · May 2026

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4. —
   Aram Verdiyan

   How AI Is Rewriting the Power Law of Venture Capital · Sep 2026

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5. —
   Ashwin Sreenivas
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6. —
   Atul Butte

   a16z Podcast: Breaking Into Bio · May 2018

   0 votes

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7. —
   Augusto Marietti

   How Kong Was Born: APIs, Hustle, and the Future of AI Infrastructure · Oct 2025

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8. —
   Bailey Richardson
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9. —
   Barbara Liskov

   Before Blockchains, There Was State Machine Replication · Jul 2026

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10. —
    Beau Woods

    Taking the Pulse on Medical Device Security · Jul 2020

    0 votes

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11. —
    Bernard J. Tyson

    a16z Podcast: The Infrastructure of Total Health · Dec 2018

    0 votes

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12. —
    Bethany Coates
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13. —
    Bharath Ramsundar
    0 votes

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14. —
    Bob Langer

    a16z Podcast: Mindsets for Engineering Biology · Oct 2017

    0 votes

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15. —
    Bob Muglia
    0 votes

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16. —
    Bob Tinker
    0 votes

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17. —
    Bobby Franklin
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18. —
    Bobby Kotick

    a16z Podcast: Gaming Goes Mainstream · Feb 2019

    0 votes

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19. —
    Brad Peterson
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20. —
    Brandon Ballinger

    a16z Podcast: Putting AI in Medicine, in Practice · Nov 2017

    0 votes

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21. —
    Brandon Cherry
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22. —
    Brennan Spellacy
    0 votes

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23. —
    Brian McCullough

    How the Internet Happened · 2 episodes

    0 votes

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24. —
    Bridgit Mendler

    Why Every Satellite Needs Earth | Northwood CEO on a16z · Mar 2026

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25. —
    Brooke Boyarsky Pratt

    The Science and Supply of GLP-1s · Jun 2024

    0 votes

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26. —
    Bryan Crowley

    a16z Podcast: Reinventing Food · Jan 2018

    0 votes

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27. —
    Bryon Hargis
    0 votes

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28. —
    Carl Pei

    Building Hardware and Taking on the Phone Giants · Apr 2023

    0 votes

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29. —
    Carlos García Ottati

    From Copilots to Agents: Rebuilding the Company Around AI · Feb 2026

    0 votes

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30. —
    Caroline Moon
    0 votes

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31. —
    Chandler Luzsicza

    The SpaceX and Tesla Playbook for Hard Tech Startups · Mar 2026

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32. —
    Chris Lyons
    0 votes

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33. —
    Chris Rippingham
    0 votes

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34. —
    Chris Schroder

    Insights from the Frontlines of Consumer Tech · Apr 2023

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35. —
    Christina Lopes
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36. —
    Christine Darden

    a16z Podcast: From Hidden Figure to Sonic BOOM · Mar 2017

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37. —
    Clayton Christensen

    a16z Podcast: Competing Against Luck · 2 episodes

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38. —
    Clifford Woolf

    a16z Podcast: The Biology of Pain · Sep 2019

    0 votes

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39. —
    Clément Delangue

    Hugging Face's CEO on Open Source AI, Model Routing, and the Future of Competition · Jul 2026

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40. —
    Colin Bryar

    Innovating While Scaling: Lessons from Amazon · May 2022

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