Into the Impossible With Brian Keating

Think like a physicist. Wonder like a human. Into the Impossible is where Cosmic Conversations happen — uniting Nobel Prize winners, iconoclasts, authors, and technologists to explore reality’s deepest questions. From AI to aliens, from biophysics to the brain, from the cosmos to the multiverse, Brian Keating, Chancellor’s Distinguished Professor of Physics at UC San Diego covers it all. If you’ve ever asked What’s out there? or What’s next?, this is where curiosity meets clarity. Learn to think like this. 🎙 Full episodes, notes & more: briankeating.com/podcast

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Most frequent guests

Eric Weinstein 24 episodes
Avi Loeb 17 episodes
James Altucher 13 episodes
Max Tegmark 9 episodes
Lawrence Krauss 7 episodes
Roger Penrose 6 episodes
Sabine Hossenfelder 6 episodes
Michael Shermer 5 episodes
Sean Carroll 4 episodes
Lee Cronin 4 episodes

Every guest on Into the Impossible With Brian Keating

334 guests, ranked by how many people never want them back.

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Michael Levin
Could Biological Robots Heal Us from the Inside? Michael Levin - #525 · Oct 2025

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Janna Levin
Janna Levin: How to Survive A Black Hole Encounter! (#093) · 2 episodes

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Douglas Murray
Can the West Survive? Douglas Murray [Ep. 491] · May 2025

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Adam Frank
Adam Frank: Are We About to Discover Alien Life? [Ep. 425] · Jun 2024

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Jordan Peterson
An Astronomer and a Philosopher Search for Truth in the Infinite | Jordan B. Peterson · 2 episodes

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Elon Musk
My conversation with Elon Musk: Cosmology, AI, and Dying on Mars (#398) · Mar 2024

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Sara Walker
Sara Walker: How the Origin of Life Could Guide Our Search for Aliens [Ep. 456] · 2 episodes

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Roman Yampolskiy
Roman Yampolskiy vs Emad Mostaque: I Was The Only Optimist - #569 · 2 episodes

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Sean Carroll
Sean Carroll: Quantum Mechanics and the Many Worlds Interpretation · 4 episodes

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Annie Jacobsen
Annie Jacobsen: How One Lab Leak Ends the World in 6 Days - #564 · Jul 2026

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Yann Lecun
Meta’s Chief AI Scientist Yann LeCun: The Path Toward Human-Level Intelligence in AI [Ep. 473] · Dec 2024

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Lee Cronin
Do We Need New Laws of Physics to Explain the Origins of Life? Brian Keating & Lee Cronin · 4 episodes

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Scott Eastwood
Brian Keating on Live Life Better with Scott Eastwood (#341) · Aug 2023

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David Sussillo
Meta NeuroScientist SHOCKED Me: Scale Alone Won’t Create Consciousness! David Sussillo - #543 · Mar 2026

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David Friedberg
Part 2 of 2: David Friedberg is All-In on Science (#298) · 2 episodes

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Brian Greene
Brian Greene: Does the Multiverse Actually Exist? (#369) · Nov 2023

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Seth Godin
Seth Godin On AI, Industrial Capitalism and Solving the Climate Crisis (#350) · 2 episodes

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Michael Saylor
Michael Saylor: The Thermodynamics of Bitcoin EXPLAINED (2021) (#393) · 2 episodes

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Cal Newport
Cal Newport: Want to Be More Productive? Do LESS (#399) · Mar 2024

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David Reich
90% of Ancient Humans Vanished. We Reconstructed Their History - David Reich - #526 · Oct 2025

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Nick Lane
The Engine That Built Life. Nick Lane - #541 · Mar 2026

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Joscha Bach
Joscha Bach: The Self Is a Story Your Brain Tells Itself - #555 · May 2026

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Stephen Wolfram
Are Humans Smart Enough to Understand the Universe? Stephen Wolfram - #506 · 3 episodes

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Max Tegmark
Max Tegmark vs. Eric Weinstein: AI, Aliens, Theories, & New Year’s Resolutions! (Repost from 2021) · 9 episodes

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Edward Frenkel
Love & Math: Edward Frenkel (#281) · Dec 2022

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Sam Harris
Sam Harris: God Did NOT Write the Bible! (#401) · Mar 2024

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David Kipping
Alien Civilizations, Exomoons, and Cool, Habitable Worlds | David Kipping [Ep. 474] · Jan 2025

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Nathalie Cabrol
Astrobiologist Says We’ve Been Searching for Aliens the Wrong Way with Nathalie Cabrol [Ep. 495] · May 2025

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Ben Shapiro
Free Will, AGI, and the Scavengers Ruining America's Future. Ben Shapiro - #512 · 3 episodes

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Balaji Srinivasan
Balaji Srinivasan: The Network State Is Eternal (#277) · Dec 2022

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John Vervaeke
Why ChatGPT Can’t Tell Compelling Stories (Yet) w/ John Vervaeke and Shawn Coyne (#402) · Mar 2024

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Noam Chomsky
Noam Chomsky on AI, Neural Networks, and the Future of Linguistics (#349) · 2 episodes

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Andrew Bustamante
Your Phone Is A Government Spy! | Andrew Bustamante [Ep. 442] · Jul 2024

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Ryan Graves
UAP Disclosure: Eyewitness encounters with Ryan Graves (#334) · Jul 2023

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Martin Rees
Martin Rees Predicts the Future of Humanity and Science! (#366) · 3 episodes

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Donald Hoffman
Donald Hoffman On Free Will, Positive Geometries of Consciousness & Spacetime [Ep. 455] · 3 episodes

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David Wolpe
Rabbi David Wolpe: Atheism, The Simulation Hypothesis, & Judaism’s view of the Multiverse! (#078) · Sep 2020

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Garry Nolan
Garry Nolan & Avi Loeb: The Science of Aliens | Brian Keating’s INTO THE IMPOSSIBLE Podcast (#343) · 2 episodes

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Philip Goff
Philip Goff: Is There Cosmic Purpose Without God? (#384) · 2 episodes

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Jay Bhattacharya
Follow Science, Not Scientists: Jay Bhattacharya (#279) · Dec 2022

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Recent episodes

632 episodes from the feed, newest first.

Carlo Rovelli: Free Will Is Real. Physics Can Prove It.
with Carlo Rovelli

Sep 2026
They Built the Quietest Place on Earth to Find Dark Matter
Sep 2026
Dark Matter Has a Problem. So Does MOND.
Sep 2026
OpenAI’s Navier–Stokes Claim: Is This What AGI Looks Like? with Emad Mostaque
with Emad Mostaque

Sep 2026
Roman Yampolskiy vs Emad Mostaque: I Was The Only Optimist - #569
with Roman Yampolskiy

Sep 2026
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with Peter McCormack

Aug 2026
The Physics Reason AI Works When It Shouldn’t - #568
Aug 2026
Engineering Chair: Most People Should Not Go To College - #567
Aug 2026
John Martinis: The Nobel Physicist Behind Macroscopic Quantum Tunneling - #566
with John Martinis

Aug 2026
Fermilab’s Scott Dodelson on Cosmology’s Crisis - #565
with Scott Dodelson

Aug 2026
Faith & the Physicist: Aliens, Astrobiology, String Theory, and the Search for Meaning
Jul 2026
Annie Jacobsen: How One Lab Leak Ends the World in 6 Days - #564
with Annie Jacobsen

Jul 2026
We Built Something We Can’t Control | A Warning from Top AI Safety Expert - #563
Jul 2026
Michael Shermer: The Only Skeptic on the Alien Task Force - #562
with Michael Shermer

Jul 2026
400K Subscribers Asked Me Anything. The Answers Got Weird.
Jul 2026
Top Astronomer: UFOs Are STILL Here - #561
Jul 2026
Nobel Economist: The Market That Lets People Die - #560
Jun 2026
Dead Cows, Aliens, & Ghosts: How Kevin Knuth Connects Them All
with Kevin Knuth

Jun 2026
Intelligent Design Theorist: AI Just Proved It Can’t Think Without Us - #559
Jun 2026
Is the White House's New UAP Council a Game Changer for Disclosure?
Jun 2026
Roman Yampolskiy: AI Can’t Be Controlled — and We’re Building It Anyway - #558
with Roman Yampolskiy

Jun 2026
Michio Kaku Went Viral On Diary of a CEO; I Had To Fact-Check
with Michio Kaku

Jun 2026
Physicist: Why I Believe in Near-Death Experiences
Jun 2026
Godlike AI Is Here! Peter Diamandis Debates Brian Keating - #557
with Peter Diamandis

Jun 2026
Two Scientists, One Question: Does Alien Life Need a Soul? - #556
May 2026