Into the Impossible With Brian Keating

Think like a physicist. Wonder like a human. Into the Impossible is where Cosmic Conversations happen — uniting Nobel Prize winners, iconoclasts, authors, and technologists to explore reality’s deepest questions. From AI to aliens, from biophysics to the brain, from the cosmos to the multiverse, Brian Keating, Chancellor’s Distinguished Professor of Physics at UC San Diego covers it all. If you’ve ever asked What’s out there? or What’s next?, this is where curiosity meets clarity. Learn to think like this. 🎙 Full episodes, notes & more: briankeating.com/podcast

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Every guest on Into the Impossible With Brian Keating

334 guests, ranked by how many people never want them back.

1. —
   John Preskill

   Part 2: John Preskill – Quantum Computing, Artificial Intelligence, and Encountering Richard Feynman (#111) · 2 episodes

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2. —
   Adam Riess

   Exploring the Mysteries of the Expanding Universe with Adam Riess · 4 episodes

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3. —
   Christof Koch

   Christof Koch Exposes the Fatal Flaw in AI Consciousness [Ep. 484] · Mar 2025

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4. —
   Daniel Dennett

   Daniel Dennett: Do We Have Free Will? [Ep. 406] · Apr 2024

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5. —
   David Chalmers

   David Chalmers: The Matrix is REAL! (#370) · 2 episodes

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6. —
   Jack Szostak
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7. —
   Lawrence Krauss

   Is There A WAR On Science? Lawrence Krauss - #505 · 7 episodes

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8. —
   Carlo Rovelli

   Carlo Rovelli: Free Will Is Real. Physics Can Prove It. · 3 episodes

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9. —
   Deepak Chopra

   Deepak Chopra: How To Know God (#124) · 2 episodes

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10. —
    Jim Al-Khalili

    Discover the Joy of Science w/ Jim Al-Khalili (#392) · 2 episodes

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11. —
    Jocelyn Bell Burnell

    Jocelyn Bell Burnell: Mentors, Pulsars & Prizes ​(#214) · Feb 2022

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12. —
    Aswath Damodaran

    What's The Real Value of Your Degree? Aswath Damodaran - #542 · Mar 2026

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13. —
    Chris Miller

    New COLD WAR Over Computer Chips? w/ Chris Miller (#391) · Feb 2024

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14. —
    Emad Mostaque

    OpenAI’s Navier–Stokes Claim: Is This What AGI Looks Like? with Emad Mostaque · 2 episodes

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15. —
    Patrick Bet-David

    Patrick Bet-David shares his next 5 moves in the event of an economic downturn (#360) · 2 episodes

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16. —
    Richard Powers

    Searching for Habitable Worlds: Richard Powers, Winner of The Pulitzer Prize (#233) · Jun 2022

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17. —
    Sam Arbesman

    The World is Made of Code! Sam Arbesman - #538 · Feb 2026

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18. —
    Terry Sejnowski

    How to train ChatGPT to serve you | AI Legend Terry Sejnowski [Ep. 475] · Jan 2025

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19. —
    Annalee Newitz

    Journalist & Author Annalee Newitz (#022) · Apr 2019

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20. —
    Caleb Scharf

    Caleb Scharf: The Ascent of Information (#163) · Jun 2021

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21. —
    Cassandra Vieten

    How Will AI Change Science? | Brian Keating & Cassandra Vieten (#379) · Dec 2023

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22. —
    Dave Asprey

    Merchants of Truth and Light: Losing the Nobel Prize - Brian Keating The Human Upgrade with Dave Asprey (#339) · Aug 2023

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23. —
    David Spergel

    David Spergel: Way of the Peaceful Cosmologist (#130) · Mar 2021

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24. —
    Dennis Prager

    Brian Keating Discusses the Ultimate Issues of Life With Dennis Prager · 2 episodes

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25. —
    Heather Heying

    Heather Heying & Bret Weinstein: A Hunter Gatherer's Guide to the 21st Century. Frogs, Family, Freedom (#186) · Oct 2021

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26. —
    Jill Tarter

    Jill Tarter – Proxima Centauri, the Drake Equation, and SETI in 2021! (#103) · Dec 2020

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27. —
    Jordan Harbinger

    How I Lost the Nobel Prize and What I Learned from the Experience w/ Jordan Harbinger · 2 episodes

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28. —
    Kip Thorne

    Bringing Astrophysics to Life Through Art with Kip Thorne and Lia Halloran (#397) · Feb 2024

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29. —
    Lia Halloran
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30. —
    Loren Grush
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31. —
    Michael Shermer

    Michael Shermer: The Only Skeptic on the Alien Task Force - #562 · 5 episodes

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32. —
    Mike Brown

    Mike Brown Lecture on Finding Planet Nine and his Journey to Redefine the Solar System · Apr 2025

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33. —
    Peter Boghossian

    Is Science in a Legitimacy Crisis? | Peter Boghossian (#346) · 2 episodes

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34. —
    Sarah Frier

    Sarah Frier : No Filter — The Inside Story of Instagram (#050) · Jun 2020

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35. —
    Steven Strogatz

    Steven Strogatz: The Infinite Power of Calculus (#158) · Jun 2021

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36. —
    Tom Bilyeu

    Tom Bilyeu: Impact Experimentalist! ​(#197) · Nov 2021

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37. —
    Alan Lightman

    Can Scientists Be Spiritual? Alan Lightman | Into The Impossible Podcast (#306) · 2 episodes

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38. —
    Andy Weir

    The Real Science of Project Hail Mary. Andy Weir - #544 · 2 episodes

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39. —
    David Marquet

    This man commanded a Billion Dollar Submarine. Let him teach you Leadership Language: David Marquet (#064) · Aug 2020

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40. —
    Freeman Dyson

    Freeman Dyson (#301) · Mar 2023

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