Mind & Matter

Weekly science podcast by neuroscientist Nick Jikomes, PhD. Long-form interviews with researchers on the brain, nutrition, metabolism, drugs and aging. Not medical advice. At M&M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it. As the host, my aim is to help you better understand how the body & mind work by curating & synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet. I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint. My beliefs:

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Every guest on Mind & Matter

280 guests, ranked by how many people never want them back.

1. —
   Charlotte Förster

   Menstrual Cycles Still Sync With the Moon, but Less Since LEDs | Charlotte Förster | 259 · Oct 2025

   0 votes

   Never again
2. —
   Chris Knobbe

   Omega-6 Rose From 1% to Nearly 12% of US Calories Since 1865, He Says | Chris Knobbe | 136 · Jan 2024

   0 votes

   Never again
3. —
   Chris Morrison

   Low-Protein Diets Make Mice Eat More and Burn More | Chris Morrison | 251 · Sep 2025

   0 votes

   Never again
4. —
   Chris Timmermann

   On DMT, the Brain Slips Into Something Much Like Dreaming | Chris Timmermann | 25 · Jun 2021

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   Never again
5. —
   Christian Luscher

   Cocaine Rewired Reward Synapses in Mice. Ketamine Didn't | Christian Lüscher | 90 · 2 episodes

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6. —
   Christoffer Clemmensen

   His Lab Paired GLP-1 With an NMDA Blocker in One Drug | Christoffer Clemmensen | 161 · 2 episodes

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7. —
   Christoph Thaiss

   Gut Bacteria Boost the Dopamine Reward From Exercise in Mice | Christoph Thaiss | 103 · Jan 2023

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8. —
   Christopher Walsh

   Why Bigger Brains Get More Mutations | Christopher Walsh | 306 · Aug 2026

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9. —
   Christopher Weikart

   These Vaccine Vials Get a Glass Layer ~1,000x Thinner Than a Hair | Christopher Weikart | 50 · Dec 2021

   0 votes

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10. —
    Clare Bryant

    An Omega-6 Fat That Rises During Fasting Dampened Inflammation | Clare Bryant | 144 · Mar 2024

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11. —
    Dan Brady

    Your Accent Was Set in Infancy, When Your Brain Merged Unused Sounds | Dan Brady | 111 · Apr 2023

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12. —
    Daniel Karlin

    Anxiety and Depression Definitions Overlap About 80% in the DSM | Daniel Karlin | 117 · Jun 2023

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13. —
    Danielle Stolzenberg

    Postpartum Psilocybin Made Mouse Moms Anxious and Harmed Pups | Danielle Stolzenberg | 270 · Dec 2025

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14. —
    David Healy

    SSRIs Can Cause Sexual Dysfunction That Lasts Years After Stopping | David Healy | 232 · Jun 2025

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15. —
    David Raubenheimer
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16. —
    David Roberson

    Lab Rodents Show More Pain When a Woman Runs the Test Than a Man | David Roberson | 52 · Jan 2022

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17. —
    Devanand Manoli

    Voles Without Oxytocin Receptors Still Formed Strong Pair Bonds | Devanand Manoli | 108 · Mar 2023

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18. —
    Diana van Heemst

    Thyroid Hormone Sets Your Metabolism and May Affect Lifespan | Diana van Heemst | 209 · Feb 2025

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19. —
    Dirk Hoffmeister

    Cut Magic Mushrooms Turn Blue as Psilocin Links Into Chains | Dirk Hoffmeister | 85 · Aug 2022

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20. —
    Douglas Wallace

    Your Mother's Mitochondrial DNA Shapes Metabolism and Disease Risk | Douglas Wallace | 283 · Mar 2026

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21. —
    Dudley Lamming

    Cutting Branched-Chain Amino Acids Extended Male Mouse Lifespan ~30% | Dudley Lamming | 92 · Oct 2022

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22. —
    Echo Rufer

    Vaping Lung Injuries Were Tied to Vitamin E Acetate Used to Dilute THC | Echo Rufer | 113 · May 2023

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23. —
    Elizabeth Hobson

    Monk Parakeets Appear to Know the Whole Group's Pecking Order | Elizabeth Hobson | 13 · Mar 2021

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24. —
    Elvira Mass

    A Mother's Obesity Reprograms Her Offspring's Liver Immune Cells in Mice | Elvira Mass | 253 · Sep 2025

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25. —
    Eske Willerslev

    Light Skin Evolved After Humans Had Already Left Africa | Eske Willerslev | 154 · Apr 2024

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26. —
    Ethan Russo

    Whole-Plant CBD Controlled Seizures at 1/5 the Dose of Pure CBD | Ethan Russo | 9 · Feb 2021

    0 votes

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27. —
    Eugene Chang

    High-Fiber Food Beat Fecal Transplants at Restoring the Gut in Mice | Eugene Chang | 240 · Jul 2025

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28. —
    Eugene Morin

    For Hunter-Gatherers, Fat Often Matters More Than Meat | Eugene Morin | 160 · Jun 2024

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29. —
    Eva Morava

    Sugars Do More Than Fuel Cells. They Help Proteins Work | Eva Morava | 207 · Feb 2025

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30. —
    Floyd Chilton

    Your Ancestry Changes How Your Body Handles Omega-3 and Omega-6 Fats | Floyd Chilton | 294 · May 2026

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31. —
    Flynn McGuire

    BPC-157 Heals Rats but Has Barely Been Tested in Humans | Flynn McGuire | 285 · Mar 2026

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32. —
    Frances Sladek

    Soybean Oil Made Mice Fatter Than Coconut Oil | Frances Sladek | 269 · Dec 2025

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33. —
    Ganesh Halade

    Too Much Omega-6 Keeps Inflammation From Shutting Off | Ganesh Halade | 266 · Dec 2025

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34. —
    Gary Churchill

    The Mice That Lost the Most Weight on Diets Lived Shorter Lives | Gary Churchill | 183 · Oct 2024

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35. —
    Gary Lewin

    This Animal Survives 18 Minutes Without Oxygen | Gary Lewin | 309 · Oct 2026

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36. —
    Gary Miller

    Pesticides Raise Parkinson's Risk, While Caffeine and Nicotine Lower It | Gary Miller | 218 · Mar 2025

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37. —
    Gary Patti

    Fructose Made Tumors Grow 4x Faster in Mice, by Way of the Liver | Gary Patti | 215 · Mar 2025

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38. —
    Gero Miesenböck

    You Need Sleep Because Your Mitochondria Leak | Gero Miesenböck | 257 · Oct 2025

    0 votes

    Never again
39. —
    Giovanni Marsicano

    Your Cannabinoid System Evolved to Store Energy for the Future | Giovanni Marsicano | 245 · Aug 2025

    0 votes

    Never again
40. —
    Giulia Santoni

    Forming a Memory Changes How DNA Is Packaged in Neurons | Giulia Santoni | 169 · Aug 2024

    0 votes

    Never again