No Priors cover art

No Priors

At this moment of inflection in technology, co-hosts Elad Gil and Sarah Guo talk to the world's leading AI engineers, researchers and founders about the biggest questions: How far away is AGI? What markets are at risk for disruption? How will commerce, culture, and society change? What’s happening in state-of-the-art in research? “No Priors” is your guide to the AI revolution. Email feedback to show@no-priors.com. Sarah Guo is a startup investor and the founder of Conviction, an investment firm purpose-built to serve intelligent software, or "Software 3.0" companies. She spent nearly a decade incubating and investing at venture firm Greylock Partners. Elad Gil is a serial entrepreneur and a startup investor. He was co-founder of Color Health, Mixer Labs (which was acquired by Twitter). He has invested in over 40 companies now worth $1B or more each, and is also author of the High Growth Handbook.

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Every guest on No Priors

150 guests, ranked by how many people never want them back.

  1. —
    Jared Quincy Davis

    The marketplace for AI compute with Jared Quincy Davis from Foundry · Aug 2024

    0 votes
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    Josh Goldman

    Predicting the Earth with Josh Goldman: How KoBold Uses AI to Find Critical Minerals · Apr 2025

    0 votes
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  5. —
    Joshua Xu

    Can AI replace the camera? with Joshua Xu from HeyGen · Jun 2024

    0 votes
  6. —
    Karan Goel

    State Space Models and Real-time Intelligence with Karan Goel and Albert Gu from Cartesia · Jun 2024

    0 votes
  7. —
    Karan Singhal

    The AI Will See You Now: Exploring Biomedical AI and Google’s Med-PaLM2 With Karan Singhal · May 2023

    0 votes
  8. —
    Kawal Gandhi

    What Google Cloud Can Teach Enterprises Developing & Rolling Out AI Tools, With Kawal Gandhi · Oct 2023

    0 votes
  9. —
    Kelvin Guu

    Personalizing AI Models with Kelvin Guu, Senior Staff Research Scientist, Google Brain · May 2023

    0 votes
  10. —
    Liam Fedus

    AI for Atoms: How Periodic Labs is Revolutionizing Materials Engineering with Co-Founder Liam Fedus · Apr 2026

    0 votes
  11. —
    Lip-Bu Tan

    Re-engineering the Semiconductor Supply Chain with Intel CEO Lip-Bu Tan · Jun 2026

    0 votes
  12. —
    Lukas Biewald

    Eradicating Machine Learning Pain Points with Weights & Biases CEO Lukas Biewald · Aug 2023

    0 votes
  13. —
    Mark Papermaster

    Competition makes for better chip design with AMD CTO Mark Papermaster · Feb 2024

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  14. —
    Matei Zaharia

    The Future is Small Models, with Matei Zaharia, CTO of Databricks · Apr 2023

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  16. —
    Max Hodak

    From Restoring Sight to Reimagining the Brain, with Max Hodak · Aug 2026

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  17. —
    Maxim Bar Kogan

    Building an AI Guardian for Enterprise with Onyx Security CEO Maxim Bar Kogan · May 2026

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  18. —
    Melisa Tokmak

    Building an Autonomous Enterprise for Real-World Services with Netic Founder Melisa Tokmak · Jul 2026

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  19. —
    Misha Laskin

    Asimov: Building An Omniscient RL Oracle with ReflectionAI’s Misha Laskin · Jul 2025

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  20. —
    Neil Tiwari

    How Capital is Powering the AI Infrastructure Buildout with Magnetar Capital Managing Director Neil Tiwari · Feb 2026

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  21. —
    Ofir Ehrlich

    Rethinking Legacy Data Infrastructure with Eon Co-Founders Ofir Ehrlich and Gonen Stein · Aug 2026

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  22. —
    Percy Liang

    What is the role of academia in modern AI research? With Stanford Professor Dr. Percy Liang · Mar 2023

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    Philipp Herzig

    SAP: Bringing the ‘Operating System’ of a Company into the AI Era with CTO Philipp Herzig · Apr 2026

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  25. —
    Ryan Noon

    AI Threats & Opportunities in Cyber Security With Material Security Co-Founder Ryan Noon · Oct 2023

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  26. —
    Simon Last

    From Coder to Manager: Navigating the Shift to Agentic Engineering with Notion Co-Founder Simon Last · Mar 2026

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  27. —
    Suhail Doshi

    The Future of AI Artistry with Suhail Doshi from Playground AI · Apr 2024

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  28. —
    Tengyu Ma

    The evolution and promise of RAG architecture with Tengyu Ma from Voyage AI · Jun 2024

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  29. —
    Tony Zhao

    Sunday Robotics: Scaling the Home Robot Revolution with Co-Founders Tony Zhao and Cheng Chi · Nov 2025

    0 votes
  30. —
    Tuhin Srivastava

    Baseten CEO Tuhin Srivastava on the AI Inference Crunch, Custom Models, and Building the Inference Cloud · 2 episodes

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Recent episodes

178 episodes from the feed, newest first.

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    with Brian Armstrong

    Sep 2026
  2. Redefining Chip Architecture with Arm CEO Rene Haas

    with Rene Haas

    Sep 2026
  3. Rethinking Legacy Data Infrastructure with Eon Co-Founders Ofir Ehrlich and Gonen Stein

    with Ofir Ehrlich

    Aug 2026
  4. From Restoring Sight to Reimagining the Brain, with Max Hodak

    with Max Hodak

    Aug 2026
  5. What Chess.com Teaches US About Superhuman Capabilities, with CEO Erik Allebest

    with Erik Allebest

    Aug 2026
  6. Chasing Trillion-Dollar Companies, Founder Ambition, Token Budgets, and Regulatory Capture with Sarah & Elad
    Aug 2026
  7. Building an Autonomous Enterprise for Real-World Services with Netic Founder Melisa Tokmak

    with Melisa Tokmak

    Jul 2026
  8. Building an Autonomous Delivery Experience with DoorDash Co-Founders Andy Fang and Stanley Tang

    with Andy Fang

    Jul 2026
  9. Travel Through the Lens of AI with with Booking.com CEO Glenn Fogel

    with Glenn Fogel

    Jul 2026
  10. How Nuclear Will Unlock Energy Abundance with Valar Atomics Founder Isaiah Taylor

    with Isaiah Taylor

    Jul 2026
  11. Really Big Test-Time Compute in AI Changes Benchmarks, Safety and Research with OpenAI Research Scientist Noam Brown

    with Noam Brown

    Jun 2026
  12. Re-engineering the Semiconductor Supply Chain with Intel CEO Lip-Bu Tan

    with Lip-Bu Tan

    Jun 2026
  13. Biohub: The Future of Biology is Open-Source with Co-Founders Mark Zuckerberg, Priscilla Chan, and Head of Science Alex Rives

    with Mark Zuckerberg

    Jun 2026
  14. We Need An Ecosystem in AI, And Every Company Can Win A Place In It
    Jun 2026
  15. Building an AI Guardian for Enterprise with Onyx Security CEO Maxim Bar Kogan

    with Maxim Bar Kogan

    May 2026
  16. The Story Behind Cerebras’ $63 Billion IPO with Founder and CEO Andrew Feldman

    with Andrew Feldman

    May 2026
  17. Pax Silica: Inside the Trump Administration’s Tech Strategy with US Under Secretary of State for Economic Affairs Jacob Helberg

    with Jacob Helberg

    May 2026
  18. Amex Global Business Travel: The World’s First AI Take Private with Long Lake CEO Alexander Taubman

    with Alexander Taubman

    May 2026
  19. Baseten CEO Tuhin Srivastava on the AI Inference Crunch, Custom Models, and Building the Inference Cloud

    with Tuhin Srivastava

    May 2026
  20. SAP: Bringing the ‘Operating System’ of a Company into the AI Era with CTO Philipp Herzig

    with Philipp Herzig

    Apr 2026
  21. Scaling Global Organizations in the Age of AI with ServiceNow Chairman and CEO Bill McDermott

    with Bill McDermott

    Apr 2026
  22. The Agentic Economy: How AI Agents Will Transform the Financial System with Circle Co-Founder and CEO Jeremy Allaire

    with Jeremy Allaire

    Apr 2026
  23. AI for Atoms: How Periodic Labs is Revolutionizing Materials Engineering with Co-Founder Liam Fedus

    with Liam Fedus

    Apr 2026
  24. Andrej Karpathy on Code Agents, AutoResearch, and the Loopy Era of AI

    with Andrej Karpathy

    Mar 2026
  25. From Coder to Manager: Navigating the Shift to Agentic Engineering with Notion Co-Founder Simon Last

    with Simon Last

    Mar 2026