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The a16z Show

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

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Every guest on The a16z Show

694 guests, ranked by how many people never want them back.

  1. —
    Lauren Richardson

    Journal Club: Finding New Antibiotics with Machine Learning, What Coronavirus Structures Tell Us · Apr 2020

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    Lee Kleinman

    a16z Podcast: All about Bike Sharing · Feb 2018

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    Lisa Hawke

    a16z Podcast: What to Know about GDPR · Apr 2018

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    Lukasz Kaiser

    Can Open Source Keep AI Power From Concentrating? · Sep 2026

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    Magi Richani

    The Future of Cheese · Jun 2023

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    Marc Andrusko

    Big Ideas 2026: The Agentic Interface · Dec 2025

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  10. —
    Margit Wennmachers

    The Secret Marketing Strategy That Built a16z: From Zero to Legendary VC Firm · 6 episodes

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  11. —
    Mark Cranney

    a16z Podcast: Pricing, Pricing, Pricing · 2 episodes

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  12. —
    Mark Leslie

    a16z Podcast: Stories and Lessons in Enterprise Sales · Jan 2019

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  15. —
    Markus Villig

    Outsmarting Uber: Why Bolt Wins in Europe · Jul 2026

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    Martin Fischer

    a16z Podcast: Construction Under Tech -- The Build · Jun 2018

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  17. —
    Matt Billmann

    a16z Podcast: Containing the Monolith -- From Microservices to DevOps · Mar 2018

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  19. —
    Matt Knight

    Securing the Black Box: OpenAI, Anthropic, and GDM Discuss · May 2024

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    Matt Tancik

    Building AI for Creators | Luma & Phota Labs · Jun 2026

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  25. —
    Mehtaab Sawhney

    OpenAI Researchers on the Future of Mathematical Reasoning · Sep 2026

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  27. —
    Michael Chow

    Founders Playbook: Lessons from Riot, Discord, & More · Jul 2024

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  28. —
    Michael Copeland

    a16z Podcast: Beyond Disruption Theory · Jul 2019

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  29. —
    Michael Duffey

    Rebuilding The American Shipyard · May 2026

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  38. —
    Mohammad Norouzi

    AI, Design, and the Power of Open Models · Jun 2026

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  39. —
    Nadia Eghbal

    Working, Making, Creating in Public... and Private · Aug 2020

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  40. —
    Naftali Harris

    a16z Podcast: Stories from the Frontlines of Synthetic Fraud · Jun 2019

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Recent episodes

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