The a16z Show

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

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Every guest on The a16z Show

694 guests, ranked by how many people never want them back.

1. —
   Nand Mulchandani

   Intelligence in the Age of AI with new CTO of the CIA · Mar 2024

   0 votes

   Never again
2. —
   Nathalie Balaban

   Journal Club: A New Path to Antibiotic Resistance · Jul 2020

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3. —
   Nick Warner

   How Do You Defend Against AI That Can Hack? · Aug 2026

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4. —
   Niels Provos
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5. —
   Nikhil Buduma

   Deploying AI in Healthcare · Mar 2026

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6. —
   Oleg Rogynskyy

   Applying AI in B2B · 2 episodes

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7. —
   Olivia Webb
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8. —
   Ollie Forsyth
   0 votes

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9. —
   Omar Khattab

   How Foundation Models Evolved: A PhD Journey Through AI's Breakthrough Era · Jan 2026

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10. —
    Owen Jennings

    What Happens When a Public Company Goes All In on AI · Apr 2026

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11. —
    Pablo Palafox

    Building AI Agents for Enterprise Operations · Jun 2026

    0 votes

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12. —
    Patrick Conway

    a16z Podcast: How to Pay for Healthcare Based on Health · Sep 2019

    0 votes

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13. —
    Paul Bakaus
    0 votes

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14. —
    Paul Daugherty
    0 votes

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15. —
    Paul Katsen

    A New Era of VR: From the Court to the Classroom · Oct 2023

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16. —
    Peter Diamandids

    The Rise of the Exponential Organization · May 2023

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17. —
    Peter Lauten
    0 votes

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18. —
    Peter Levine

    The Open Source CIO · 2 episodes

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19. —
    Phillip Buckendorf

    The Software Crisis Behind America's Infrastructure · Apr 2025

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20. —
    Prasad Akella

    a16z Podcast: Automation + Work, Human + Machine · Nov 2018

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21. —
    Preethi Kasireddy
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22. —
    Rajeev Singh

    a16z Podcast: The Business of Healthcare · Mar 2017

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23. —
    Rajeev Venkayya

    On Vaccines and Vaccinology, in COVID and Beyond · Aug 2020

    0 votes

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24. —
    Ram Palaniappan
    0 votes

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25. —
    Ram Palianappan

    The Hustler's Guide to Getting Paid · Sep 2019

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26. —
    Richard Green
    0 votes

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27. —
    Rob Goodman
    0 votes

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28. —
    Robert Gaucher
    0 votes

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29. —
    Robert Stromberg

    a16z Podcast: Building Worlds with VR, Art, and Narrative · Jan 2017

    0 votes

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30. —
    Robin Rombach
    0 votes

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31. —
    Robin Weisnman
    0 votes

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32. —
    Russ Altman

    a16z Podcast: The Genetics Of Drug Delivery · Mar 2017

    0 votes

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33. —
    Russ Fradin

    The $700 Billion AI Productivity Problem No One's Talking About · Dec 2025

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34. —
    Ryan McEntush
    0 votes

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35. —
    Ryan Tseng

    The Future of Drone Warfare · Apr 2025

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36. —
    Salim Ismail
    0 votes

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37. —
    Sam Williams
    0 votes

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38. —
    Santiago Suarez

    The Fintech Playbook for Latin America · Jun 2026

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39. —
    Saswat Panigrahi

    The Road to Autonomous Vehicles: Are We There Yet? · Jun 2023

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40. —
    Sateesh Talluri
    0 votes

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