The a16z Show

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

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Every guest on The a16z Show

694 guests, ranked by how many people never want them back.

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Vijay Balasubramaniyan
The Deepfake Dilemma: The Technology, Policy, and Economy · 2 episodes

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Vijay Bolina

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Wei Luo
a16z Podcast: Exploding the Map · Sep 2017

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Will Bitsky

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Yafah Edelman
The 2045 Superintelligence Timeline: Epoch AI’s Data-Driven Forecast · Nov 2025

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Yogi Roth
a16z Podcast: Eyeballs on the Game · Oct 2018

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Yoko Li
The $3 Trillion AI Coding Opportunity · Dec 2025

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Zabie Elmgren

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Zach Xia

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Zack Weiner

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de la Garza
Cybercrime, Incorporated · Jul 2020

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Iman Abuzeid
Nursing Today, From the Bedside and Beyond · Nov 2019

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Magic Johnson
How Magic Johnson Built a Billion-Dollar Portfolio in 30 Years · Feb 2026

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Keller Rinaudo Cliffton
a16z Podcast: Drones for Delivery in Healthcare · Nov 2016

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Recent episodes

1000 episodes from the feed, newest first.

Greg Brockman on Why OpenAI Says We’re Entering the AGI Era
with Greg Brockman

Sep 2026
World Models, Robotics, and the Future of 3D AI
with Justin Johnson

Sep 2026
Why Companies Are Becoming a Series of Loops | Anish Acharya on Lenny’s Podcast
with Anish Acharya

Sep 2026
What It Takes to Build a Startup | Andrew Chen & Matt Perault
with Andrew Chen

Sep 2026
How AI Is Rewriting the Power Law of Venture Capital
with Aram Verdiyan

Sep 2026
Who Grades the AI Models? | Ben Horowitz & Rayan Krishnan
with Rayan Krishnan

Sep 2026
OpenAI Researchers on the Future of Mathematical Reasoning
with Mehtaab Sawhney

Sep 2026
Can Open Source Keep AI Power From Concentrating?
with Lukasz Kaiser

Sep 2026
Your AI Doctor Is Coming | Julie Yoo
with Julie Yoo

Sep 2026
Aaron Levie on Why Open AI Wins
with Aaron Levie

Sep 2026
Fei Fei Li: The Race to Build World Models For AI
with Fei Fei Li

Sep 2026
The $100B Niches Hiding Inside Payments
with Max Levchin

Sep 2026
Inside Moderna’s Personalized Cancer Vaccine
with Stéphane Bancel

Sep 2026
Daniel Litt: The Mathematician's Guide to AI
with Daniel Litt

Sep 2026
Gavin Baker: Why AI Demand Is Outrunning Compute Supply
with Gavin Baker

Aug 2026
Why a16z Launched the Machine Age Fund | Jen Kha
with Jen Kha

Aug 2026
Why 1,200 AI Agents Started Working Together | Ryan Greenblatt
with Ryan Greenblatt

Aug 2026
The Infrastructure Behind the Machine Age
with Martin Casado

Aug 2026
Inside Cursor: The Anatomy of a Generational Startup
with Martin Casado

Aug 2026
The State of AI: Macro, Apps, and Consumer
with Anish Acharya

Aug 2026
The New Economics of AI | Martin Casado & Steven Sinofsky
with Martin Casado

Aug 2026
Why Medical AI Needs a Referee | Protege's Engy Ziedan
with Engy Ziedan

Aug 2026
Martin Casado on Where the Value Is Going in AI
with Martin Casado

Aug 2026
Microsoft's Deputy CISO on Securing AI Agents
with Aaron Zollman

Aug 2026
How Global Networks Are Reshaping Startup Success
with Angela Strange

Aug 2026