Unsupervised Learning with Jacob Effron

We probe the sharpest minds in AI in search for the truth about what’s real today, what will be real in the future and what it all means for businesses and the world. If you’re a builder, researcher or investor navigating the AI world, this podcast will help you deconstruct and understand the most important breakthroughs and see a clearer picture of reality. Follow this show and consider enabling notifications to stay up to date on our latest episodes. Unsupervised Learning is a podcast by Redpoint Ventures, an early-stage venture capital fund that has invested in companies like Snowflake, Stripe, and Mistral. Hosted by Redpoint investor Jacob Effron alongside Patrick Chase, Jordan Segall and Erica Brescia.

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Most frequent guests

Ari Morcos 2 episodes

Every guest on Unsupervised Learning with Jacob Effron

89 guests, ranked by how many people never want them back.

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Dario Amodei
Ep 20: Anthropic CEO Dario Amodei on the Future of AGI, Leading Anthropic, and AI Doom Chances · Oct 2023

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Aravind Srinivas
Ep 23: Perplexity CEO Aravind Srinivas on the future of Search, OpenAI Wrappers and Using AI to Talk to Loved Ones · Dec 2023

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Sam Altman
Bonus Episode: Sam Altman (CEO, OpenAI) Talks GPT-4o and Predicts the Future of AI · May 2024

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Yann Lecun
Ep 86: Yann LeCun on Leaving Meta, Breaking The LLM Paradigm, & Why Hinton is Wrong · May 2026

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Dylan Patel
Ep 53: SemiAnalysis Founder Dylan Patel on New AI Regulations, Future of Chinese AI & xAI’s Scrappy Surge to Hyperscale · Jan 2025

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Noam Shazeer
Ep 58: Google Researchers Noam Shazeer and Jack Rae on Scaling Test-time Compute, Reactions to Ilya & AGI · Mar 2025

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Noam Brown
Ep 49: OpenAI Researcher Noam Brown Unpacks the Full Release of o1 and the Path to AGI · Dec 2024

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Daphne Koller
Ep 10: Insitro CEO Daphne Koller on Using ML to Change Drug Discovery · Jun 2023

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Daniel Kokotajlo
Ep 65: Co-Authors of AI-2027 Daniel Kokotajlo and Thomas Larsen On Their Detailed AI Predictions for the Coming Years · May 2025

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Sal Khan
Ep 63: Khan Academy Founder/CEO on Salman Khan on Classrooms in 20 years, Rolling out to 1.4M Users & Sal’s Hopes for AI Education · Apr 2025

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Scott Belsky
Ep 36: Adobe CPO Scott Belsky on How AI Will Transform Creative Workflows · Jun 2024

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Thomas Dohmke
Ep 39: Github CEO Thomas Dohmke on Building Copilot, Scaling to 1.2M Users and the Future of Code · Jul 2024

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Aidan Gomez
Ep 62: CEO of Cohere Aidan Gomez on Scaling Limits Emerging, AI Use-cases with PMF & Life After Transformers · Apr 2025

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Amjad Masad
Ep 26: Replit Founder Amjad Masad on the 1000x Engineer, ChatBots are Overhyped and Why We Don’t Really Have True Open-Source Models · Feb 2024

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Arthur Mensch
Ep 31: CEO and Co-Founder of Mistral Arthur Mensch on the Next Frontiers for LLMs, Why Open Source Will Prevail and AI Safety · Mar 2024

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Arvind Narayanan
Ep 54: Princeton Researcher Arvind Narayanan on the Limitations of Agent Evals, AI’s Societal Impact & Important Lessons from History · Jan 2025

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Brendan Foody
Ep 68: CEO of Mercor Brendan Foody on Evals Replacing Knowledge Work, AI x Hiring Today & the Future of Data Labeling · Jun 2025

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David Luan
Ep 55: Head of Amazon AGI Lab David Luan on DeepSeek’s Significance, What’s Next for Agents & Lessons from OpenAI · Feb 2025

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Des Traynor
Ep 25: Intercom Co-Founder Des Traynor on Building Winning AI Strategy and Where We Are in the AI Adoption Curve · Jan 2024

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Dianne Penn
Ep 77: Anthropic’s Dianne Na Penn on Opus 4.5, Rethinking Model Scaffolding & Safety as a Competitive Advantage · Dec 2025

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Douwe Kiela
Ep 43: CEO/Co-Founder of Contextual AI Douwe Kiela Reaction to o1, What’s Next in Reasoning and Innovations in Post-Training · Sep 2024

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Edwin Chen
Ep 80: CEO of Surge AI Edwin Chen on Why Frontier Labs Are Diverging, RL Environments & Developing Model Taste · Dec 2025

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Eric Ries
Ep 34: Eric Ries and Jeremy Howard (Answer.ai) on the Biggest Mistakes AI Founders are Making and Building the Bell Labs of AI · May 2024

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Lin Qiao
Ep 50: Fireworks CEO Lin Qiao on Why There Won’t be a Single Model, Will Hyperscalers Win Inference & AI Use-cases with PMF · Dec 2024

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Logan Kilpatrick
Ep 24: OpenAI Head of DevRel Logan Kilpatrick on The Best ChatGPT Use Cases, Future of Agents, and Google Gemini · Jan 2024

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Marc Benioff
Ep 52: Marc Benioff Responds to Satya and Unpacks the Agentic Era · Jan 2025

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Mario Schlosser
Ep 27: Oscar Co-Founder Mario Schlosser on How LLMs Can Be Used in Healthcare Today and The Path to AI Doctors · Feb 2024

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Max Junestrand
Ep 67: Max Junestrand (CEO, Legora) on Differentiating and Pricing AI Apps & How the Legal Industry Will Evolve · May 2025

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Mikey Shulman
Ep 35: CEO of Suno Mikey Shulman on Future of Music with AI, Tactics for Model Eval and Solving the Blank Canvas Problem · May 2024

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Peter Deng
Ep 73: General Partner of Felicis Peter Deng on on AI Pricing Tactics, Reaction to GPT-5 & Why Voice is Underrated · Aug 2025

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Rahul Vohra
Ep 30: Superhuman CEO Rahul Vohra on the Future of Email with AI and the Role Agents Will Play · Mar 2024

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Richard Socher
Ep 5: You.com CEO Richard Socher on The Future of Search, Open Source Models and AGI · Apr 2023

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Clara Shih
Ep 29: Salesforce AI CEO Clara Shih on Future of Slack, How Gucci Uses AI and Working with Marc Benioff · Mar 2024

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Cristóbal Valenzuela
Ep 38: Runway CEO Cristobal Valenzuela on the Next Frontiers for AI Media and The Role of Human Taste in AI Filmmaking · Jul 2024

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Rahul Roy-Chowdhury
Ep 42: CEO of Grammarly Rahul Roy-Chowdhury on the Future of Communication, Impact of LLMs and How Grammarly Does Eval · Sep 2024

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Andy Beck
Ep 13: PathAI CEO Dr. Andy Beck on the Future of AI in Medical Diagnosis · Jul 2023

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Harrison Chase
Ep 28: LangChain CEO Harrison Chase on the Current State of Eval and Agents and The LLM Apps that Will Define 2024 · Feb 2024

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Keith Peiris
Ep 19: Tome CEO Keith Peiris on Disrupting Powerpoint and Scaling To Millions of Users · Sep 2023

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Edo Liberty
Ep 32: CEO and Founder of Pinecone Edo Liberty on Pioneering Vector Databases, Barriers to Productionalizing Models and Why What’s Happening with GPUs is Not Sustainable · Apr 2024

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Erik Bernhardsson
Ep 21: Modal CEO Erik Bernhardsson on Bringing Development to the Cloud, the GPU Market, and GenAI Music · Oct 2023

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