No Priors

At this moment of inflection in technology, co-hosts Elad Gil and Sarah Guo talk to the world's leading AI engineers, researchers and founders about the biggest questions: How far away is AGI? What markets are at risk for disruption? How will commerce, culture, and society change? What’s happening in state-of-the-art in research? “No Priors” is your guide to the AI revolution. Email feedback to show@no-priors.com. Sarah Guo is a startup investor and the founder of Conviction, an investment firm purpose-built to serve intelligent software, or "Software 3.0" companies. She spent nearly a decade incubating and investing at venture firm Greylock Partners. Elad Gil is a serial entrepreneur and a startup investor. He was co-founder of Color Health, Mixer Labs (which was acquired by Twitter). He has invested in over 40 companies now worth $1B or more each, and is also author of the High Growth Handbook.

Website

Every guest on No Priors

150 guests, ranked by how many people never want them back.

—
Elias Torres
Revolutionizing Customer Success with Agency’s Elias Torres · Dec 2024

0 votes
—
Emad Mostaque
How can we make sure that everyone has access to AI? Can small models outperform large models? With Stability AI’s Emad Mostaque · Feb 2023

0 votes
—
Eric Glyman
How AI can help build smarter systems for every team with Eric Glyman and Karim Atiyeh of Ramp · Aug 2024

0 votes
—
Eric Simons
Bolt’s Eric Simons on Enabling Everyone to Generate Websites with AI · Dec 2024

0 votes
—
Erik Allebest
What Chess.com Teaches US About Superhuman Capabilities, with CEO Erik Allebest · Aug 2026

0 votes
—
Fidji Simo
What's for Dinner? AI-Driven Commerce with Instacart CEO Fidji Simo · Jun 2023

0 votes
—
Frank Slootman
Bringing AI to the Data Cloud, with Snowflake's CEO Frank Slootman · Jun 2023

0 votes
—
Garry Tan
How YC fosters AI Innovation with Garry Tan · May 2024

0 votes
—
Guillermo Rauch
AI Superpowers for Frontend Developers, with Vercel Founder/CEO Guillermo Rauch · Aug 2023

0 votes
—
Howie Liu
Low-Code in the Age of AI and Going Enterprise, with Howie Liu from Airtable · Jul 2024

0 votes
—
Jesse Zhang
AI Agents Talking to AI Agents: Reinventing Commerce with Decagon CEO Jesse Zhang · 2 episodes

0 votes
—
Karim Atiyeh

0 votes
—
Laura Deming
Why Cryopreservation is No Longer Science Fiction with Until Co-founder and CEO Laura Deming · Jan 2026

0 votes
—
Luis von Ahn
Gaming as the Future of Education with Duolingo CEO Luis von Ahn · May 2025

0 votes
—
Mati Staniszewski
The Future of Voice AI: Agents, Dubbing, and Real-Time Translation with ElevenLabs Co-Founder Mati Staniszewski · Dec 2025

0 votes
—
Matt MacInnis
Using AI to evaluate employee performance with Rippling’s COO Matt MacInnis · Sep 2024

0 votes
—
Matthew Prince
The Shifting Value of Content in the AI Age with Cloudflare CEO Matthew Prince · Aug 2025

0 votes
—
Mikey Shulman
Music consumers are becoming the creators with Suno CEO Mikey Shulman · May 2024

0 votes
—
Nikesh Arora
The Impact of AI, from Business Models to Cybersecurity, with Palo Alto Networks CEO Nikesh Arora · Oct 2025

0 votes
—
Olivier Pomel
What happens to Observability If Code is AI-Generated? The Potential for AI in DevOps, with Datadog Co-founder/CEO Olivier Pomel · Jun 2023

0 votes
—
Parker Conrad
Why Platforms Win and Point Solutions Fail with Rippling CEO Parker Conrad · Jul 2025

0 votes
—
Pedro Franceschi
Innovating Spend Management through AI with Pedro Franceschi from Brex · Aug 2024

0 votes
—
Priscilla Chan

0 votes
—
Qasar Younis
The Operating System for Self Driving Cars (and Tanks, and Trucks...) With Qasar Younis and Peter Ludwig of Applied Intuition · Jun 2025

0 votes
—
Scott Wu
Cognition’s Scott Wu on how Devin, the AI software engineer, will work for you · May 2024

0 votes
—
Shiv Rao
Conversations Are the Source of Truth in Healthcare with Abridge CEO Shiv Rao · Mar 2025

0 votes
—
Shyam Sankar
How Palantir’s AI Bet is Revolutionizing Defense and Beyond, with CTO Shyam Sankar · Jul 2023

0 votes
—
Sridhar Ramaswamy
Meet Snowflake Intelligence: A Personalized Enterprise Intelligence Agent with Sridhar Ramaswamy · 2 episodes

0 votes
—
Zach Dell
Unlocking the Road to Energy Abundance with Base Power CEO and Co-Founder Zach Dell · Oct 2025

0 votes
—
Zach Lloyd
Reinventing the Developer Terminal with Warp Co-Founder and CEO Zach Lloyd · Oct 2025

0 votes
—
Brett Adcock
The argument for humanoid AI robots with Brett Adcock from Figure · Apr 2024

0 votes
—
Clara Shih
AI is the new enterprise UI with Clara Shih, CEO Salesforce AI · Dec 2023

0 votes
—
Cristóbal Valenzuela
What does AI-powered content creation look like? with Runway ML’s Cristobal Valenzuela · Feb 2023

0 votes
—
Jeremy Allaire
The Agentic Economy: How AI Agents Will Transform the Financial System with Circle Co-Founder and CEO Jeremy Allaire · Apr 2026

0 votes
—
Kanjun Qiu
AI Agents That Reason and Code with Imbue Co-Founders Kanjun Qiu and Josh Albrecht · Nov 2023

0 votes
—
Keller Rinaudo Cliffton
Founder Stories: What’s behind the largest commercial autonomous system on earth? With Zipline’s Keller Rinaudo Cliffton · Feb 2023

0 votes
—
Kyle Vogt
Building Hard Tech in Hard Markets: Kyle Vogt on Cruise, Twitch, and The Bot Company · Feb 2025

0 votes
—
Noubar Afeyan
Building the Platform for Scientific Breakthrough, with Noubar Afeyan of Moderna and Flagship Pioneering · Feb 2025

0 votes
—
Brian Schimpf
AI & Defense Technology with Anduril CEO Brian Schimpf · Jun 2023

0 votes
—
Dave Baszucki
Introducing 4D Creation Open Beta: NPCs, 4D Worlds, and the Future of Gaming with Roblox CEO Dave Baszucki · Feb 2026

0 votes

Recent episodes

178 episodes from the feed, newest first.

Coinbase’s Everything Exchange: Agentic Finance, Stablecoins, and Tokenization with CEO Brian Armstrong
with Brian Armstrong

Sep 2026
Redefining Chip Architecture with Arm CEO Rene Haas
with Rene Haas

Sep 2026
Rethinking Legacy Data Infrastructure with Eon Co-Founders Ofir Ehrlich and Gonen Stein
with Ofir Ehrlich

Aug 2026
From Restoring Sight to Reimagining the Brain, with Max Hodak
with Max Hodak

Aug 2026
What Chess.com Teaches US About Superhuman Capabilities, with CEO Erik Allebest
with Erik Allebest

Aug 2026
Chasing Trillion-Dollar Companies, Founder Ambition, Token Budgets, and Regulatory Capture with Sarah & Elad
Aug 2026
Building an Autonomous Enterprise for Real-World Services with Netic Founder Melisa Tokmak
with Melisa Tokmak

Jul 2026
Building an Autonomous Delivery Experience with DoorDash Co-Founders Andy Fang and Stanley Tang
with Andy Fang

Jul 2026
Travel Through the Lens of AI with with Booking.com CEO Glenn Fogel
with Glenn Fogel

Jul 2026
How Nuclear Will Unlock Energy Abundance with Valar Atomics Founder Isaiah Taylor
with Isaiah Taylor

Jul 2026
Really Big Test-Time Compute in AI Changes Benchmarks, Safety and Research with OpenAI Research Scientist Noam Brown
with Noam Brown

Jun 2026
Re-engineering the Semiconductor Supply Chain with Intel CEO Lip-Bu Tan
with Lip-Bu Tan

Jun 2026
Biohub: The Future of Biology is Open-Source with Co-Founders Mark Zuckerberg, Priscilla Chan, and Head of Science Alex Rives
with Mark Zuckerberg

Jun 2026
We Need An Ecosystem in AI, And Every Company Can Win A Place In It
Jun 2026
Building an AI Guardian for Enterprise with Onyx Security CEO Maxim Bar Kogan
with Maxim Bar Kogan

May 2026
The Story Behind Cerebras’ $63 Billion IPO with Founder and CEO Andrew Feldman
with Andrew Feldman

May 2026
Pax Silica: Inside the Trump Administration’s Tech Strategy with US Under Secretary of State for Economic Affairs Jacob Helberg
with Jacob Helberg

May 2026
Amex Global Business Travel: The World’s First AI Take Private with Long Lake CEO Alexander Taubman
with Alexander Taubman

May 2026
Baseten CEO Tuhin Srivastava on the AI Inference Crunch, Custom Models, and Building the Inference Cloud
with Tuhin Srivastava

May 2026
SAP: Bringing the ‘Operating System’ of a Company into the AI Era with CTO Philipp Herzig
with Philipp Herzig

Apr 2026
Scaling Global Organizations in the Age of AI with ServiceNow Chairman and CEO Bill McDermott
with Bill McDermott

Apr 2026
The Agentic Economy: How AI Agents Will Transform the Financial System with Circle Co-Founder and CEO Jeremy Allaire
with Jeremy Allaire

Apr 2026
AI for Atoms: How Periodic Labs is Revolutionizing Materials Engineering with Co-Founder Liam Fedus
with Liam Fedus

Apr 2026
Andrej Karpathy on Code Agents, AutoResearch, and the Loopy Era of AI
with Andrej Karpathy

Mar 2026
From Coder to Manager: Navigating the Shift to Agentic Engineering with Notion Co-Founder Simon Last
with Simon Last

Mar 2026