The Human Upgrade

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio , he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

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Every guest on The Human Upgrade

842 guests, ranked by how many people never want them back.

1. —
   Mario Brainovic

   Upgrade Spotlight: Unlocking the Secrets of Water Energy, Frequency & Vibration - Mario Brainovic : 1055 · May 2023

   0 votes

   Never again
2. —
   Mark Alexander

   How Resistance Training and the ARX Fit System Will Revolutionize Your Workout - Mark Alexander - #422 · Aug 2017

   0 votes

   Never again
3. —
   Mark Atkinson

   Be Unlimited - Dr Mark Atkinson : 472 · 3 episodes

   0 votes

   Never again
4. —
   Mark Divine

   Downward Dog Like a Real Life Warrior One with Mark Divine · 2 episodes

   0 votes

   Never again
5. —
   Mark Gober

   The Science of Consciousness: What’s Beyond the Brain? | Mark Gober : 1262 · Mar 2025

   0 votes

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6. —
   Mark Goulston

   Why Youth Mental Health & Suicide Matters to Everyone – Dr. Mark Goulston : 1003 · Dec 2022

   0 votes

   Never again
7. —
   Mark Harper

   Chilling Secrets: Unlocking Cold-Water Therapy's Power with Dr. Mark Harper : 1096 · 2 episodes

   0 votes

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8. —
   Mark Hunter

   #75 Heavy Metal Bulletproof with Mark Hunter · Nov 2013

   0 votes

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9. —
   Mark Lintern

   Rethinking Cancer: Inflammation, Infections, and Mitochondrial Insights with Mark Lintern : 1155 · Apr 2024

   0 votes

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10. —
    Mary Newport

    Alzheimer’s Prevention: Unlock Brain Health with Keto & Fats - Dr. Mary Newport : 1192 · Aug 2024

    0 votes

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11. —
    Maryam Henein
    0 votes

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12. —
    Master Mingtong Gu

    Master Your Energy to Transform Your Life – Master Mingtong Gu with Dave Asprey – #833 : 833 · Jun 2021

    0 votes

    Never again
13. —
    Mastin Kipp

    How to Know Your Purpose and Avoid Trauma - Mastin Kipp : 501 · Jun 2018

    0 votes

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14. —
    Matt Gallant

    Sleep Breakthroughs, Stacks & Solutions – Matt Gallant : 996 · 2 episodes

    0 votes

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15. —
    Matt Whitmore
    0 votes

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16. —
    Matt Zemon

    The New Science Behind Psychedelics, Exotic Shrooms, & Daily Flow-States | Matt Zemon : 1280 · May 2025

    0 votes

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17. —
    Mattias Ribbing

    Mastering Memory with Mattias Ribbing – Podcast #140 · Jul 2014

    0 votes

    Never again
18. —
    Melinda Culver

    Uncovering the Science of MCTs & Bulletproofing Your Pets with Melinda Culver – #151 · Sep 2014

    0 votes

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19. —
    Micah Lowe

    Ozone Therapy: Your New Favorite Biohack – Micah Lowe with Dave Asprey : 858 · Sep 2021

    0 votes

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20. —
    Michael B. Curry

    Love is the Way: Hope for Ourselves and Others – Bishop Michael B. Curry with Dave Asprey : 764 · Nov 2020

    0 votes

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21. —
    Michael Brandt

    Upgrade Spotlight: Enhance Your Performance with Ketones - Michael Brandt : 1191 · Aug 2024

    0 votes

    Never again
22. —
    Michael Christopher

    The Skin Mistakes That Age You Fast and Kill You Slow | Dr. Michael Christopher : 1485 · Jun 2026

    0 votes

    Never again
23. —
    Michael Fishman

    #58 Food Choices, Willpower & Sugar Cravings with Michael Fishman · Aug 2013

    0 votes

    Never again
24. —
    Michael Ford

    Hacking Thyroid, Autoimmunity & Aging – Interventions With Dave – Michael Ford : 918 · Mar 2022

    0 votes

    Never again
25. —
    Michael Rubino

    Detox Your Home: How to Improve Indoor Air Quality & Get Rid of Mold – Michael Rubino : 1036 · Mar 2023

    0 votes

    Never again
26. —
    Michael Salguero

    Why Quality Meat Matters for You and the Planet - Michael Salguero : 543 · Nov 2018

    0 votes

    Never again
27. —
    Michael Vassar

    Podcast #14: Michael Vassar of The Singularity Institute · Dec 2011

    0 votes

    Never again
28. —
    Michal Mor

    How to Hack Your Metabolism and Power Your Energy – Michal Mor, Ph.D. : 962 · Aug 2022

    0 votes

    Never again
29. —
    Michelle Perro

    Gut Health Matters At Every Age: Pediatrician, Michelle Perro : 511 · Jul 2018

    0 votes

    Never again
30. —
    Mike Adams

    Patrolling with the Health Ranger, Mike Adams · Jul 2016

    0 votes

    Never again
31. —
    Mike Dow

    Bigger Brains from Adult Play and Hypnosis: Dr. Mike Dow : 525 · Sep 2018

    0 votes

    Never again
32. —
    Mike McIntyre

    Mini Episode: Achieve Deeper Healing with Innovative Light Therapy - Mike McIntyre : 1164 · May 2024

    0 votes

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33. —
    Miriam Merad

    Inflammation’s Ties to Fasting, Cancer and Covid – Dr. Miriam Merad with Dave Asprey : 783 · Jan 2021

    0 votes

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34. —
    Miss Jaiya

    Beyond the Bedroom: Hacking Your Erotic Blueprint - Miss Jaiya : 1112 · Dec 2023

    0 votes

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35. —
    Mistress Natalie

    50 Shades of Dave with Mistress Natalie · Sep 2016

    0 votes

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36. —
    Moha Bensofia

    How to Increase Neuroplasticity and Strengthen Your Brain – Moha Bensofia : 1031 · Mar 2023

    0 votes

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37. —
    Moira Forbes

    How Entrepreneur and Media Mogul, Moira Forbes, says “No.” : 499 · Jun 2018

    0 votes

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38. —
    Molly Maloof

    How To Hack Your Brain's Missing Youth Molecule | Molly Maloof : 1469 · 3 episodes

    0 votes

    Never again
39. —
    Monica Hershaft

    Stay Sick or Eat Meat? Facing a Vegan Crisis – Monica Hershaft : 897 · Jan 2022

    0 votes

    Never again
40. —
    Mr. Noots

    Hack Your Neurochemistry with Customized Nootropics – Mr. Noots & Matt Gallant : 861 · Sep 2021

    0 votes

    Never again