The Human Upgrade

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio , he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

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Every guest on The Human Upgrade

842 guests, ranked by how many people never want them back.

1. —
   Rachelle Copeland

   Hacking Injury Healing from the Inside Out – Interventions With Dave – Rachelle Copeland : 1006 · Dec 2022

   0 votes

   Never again
2. —
   Raj Attariwala

   Do You Have Cancer? A New Whole-Body MRI Scan Sees Everything – Dr. Raj Attariwala : 989 · Oct 2022

   0 votes

   Never again
3. —
   Rajshree Patel

   How to Biohack & Optimize Your Inner Life – Rajshree Patel : 632 · Oct 2019

   0 votes

   Never again
4. —
   Ralph Moss

   A Second Opinion: Laetrile at Sloan-Kettering with Ralph Moss & Eric Merola – #155 · Sep 2014

   0 votes

   Never again
5. —
   Ravé Mehta

   Ravé Mehta - Fear & Vulnerability Hacks: #303 · Apr 2016

   0 votes

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6. —
   Reed Davis

   Reed Davis: Master Your Lab Results - #266 · Dec 2015

   0 votes

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7. —
   Reichart Von Wolfsheild

   #46: Reichart Von Wolfsheild - Bulletproof Your Systems · Jun 2013

   0 votes

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8. —
   Richard Nikoley

   #124 Resistant Starch Revealed with Richard Nikoley and Tim Steele · 2 episodes

   0 votes

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9. —
   Richard Veech

   Exclusive: Interview with Ketone Expert Dr. Richard Veech - #299 · Apr 2016

   0 votes

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10. —
    Ritchie Shoemaker

    #126 Dr. Ritchie Shoemaker on Surviving Mold · May 2014

    0 votes

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11. —
    Rob Whitfield

    Save Face: Non-Surgical Solutions From a Plastic Surgeon – Dr. Rob Whitfield : 1132 · Feb 2024

    0 votes

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12. —
    Robby Sansom

    How Regenerative Systems Save the Soil, Animals & You – Robby Sansom : 970 · Aug 2022

    0 votes

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13. —
    Robert Cooper

    Robert Cooper: Rewiring Your Brain & Creating New Habits #261 · Nov 2015

    0 votes

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14. —
    Robert Edward Grant

    Exploring Polymathy, Biohacking, and Consciousness with Robert Edward Grant : 1195 · Aug 2024

    0 votes

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15. —
    Robert Goldman

    Solving the Problem of Aging with Dr. Robert Goldman : 556 · Jan 2019

    0 votes

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16. —
    Robert Hamilton Owens

    Stronger at 68: 7 Marathons in 7 Days – Robert Hamilton Owens : 660 · Jan 2020

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17. —
    Robert Kushner

    Hype or Hope? Semaglutide Changes the Weight Game – Dr. Robert Kushner : 896 · Jan 2022

    0 votes

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18. —
    Robert Lee

    Robert Lee: Breathing for Performance, Focus, & Freediving – #185 · Jan 2015

    0 votes

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19. —
    Robert Lufkin

    Lies I Taught In Medical School - Dr. Robert Lufkin : 1179 · Jul 2024

    0 votes

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20. —
    Robert Rowen

    Your Ultimate Guide to Ozone Therapy – Dr. Robert Rowen with Dave Asprey : 697 · 3 episodes

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21. —
    Robert Soler

    Transform Your Indoors with Human Compatible™ Lighting – Robert Soler & Dave Asprey Hack LEDs : 704 · May 2020

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22. —
    Robert Whitfield

    How Breast Implants Compromise Your Health and Make You Sick – Dr. Robert Whitfield MD : 1043 · Apr 2023

    0 votes

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23. —
    Robyn Benson

    Dr. Robyn Benson: Healing with Oxygen, Hydration, & Biohacking - #194 · Feb 2015

    0 votes

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24. —
    Robyn Openshaw

    Does Food Really Have a Vibration? Robyn Openshaw - #438 · Oct 2017

    0 votes

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25. —
    Rocky Patel

    Podcast #32: Hacking your Heart and Preventing Diabetes with Dr. Rocky Patel · Nov 2012

    0 votes

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26. —
    Roger Lawson

    Podcast #12: Sexification with Roger Lawson · Nov 2011

    0 votes

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27. —
    Roger Love

    Biohack Your Voice for Better Communication Instantly – Roger Love with Dave Asprey : 752 · Oct 2020

    0 votes

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28. —
    Roland Peralta

    The Real Story Behind Hair Loss and the Revolutionary Approach to Treating It - Roland Peralta - #420 · Aug 2017

    0 votes

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29. —
    Rollin McCraty

    Heart Coherence Unveiled: A Journey with Rollin McCraty : 1094 · Oct 2023

    0 votes

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30. —
    Ron Hunninghake

    Vitamin C Is Taking The Fight To The Big "C" – Dr. Ron Hunninghake - #379 · Jan 2017

    0 votes

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31. —
    Ronda Collier

    #84 Hacking Stress with HRV Sense and Ronda Collier · 2 episodes

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32. —
    Rowena Gates

    The Anti-Aging Science Behind the NanoVi Device - Rowena Gates & Hans Eng - #416 · Jul 2017

    0 votes

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33. —
    Rudolph Tanzi

    The Rock Star Scientist of Alzheimer’s on How to Stop Neuroinflammation – Dr. Rudolph Tanzi with Dave Asprey : 707 · Jun 2020

    0 votes

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34. —
    Ryan Blaser

    Your Home Is Making You Sick: Biohack Your Living Space with Toxin Testing - Ryan Blaser : 1082 · Aug 2023

    0 votes

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35. —
    Ryan Cummins

    How to Upgrade Your Gratitude with Charity: Ryan Cummins : 523 · Sep 2018

    0 votes

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36. —
    Ryan Estis

    On leadership: How to do What You Love - Ryan Estis : 521 · Aug 2018

    0 votes

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37. —
    Saba Yussouf

    Super Detergent, Nanobubbles & Living Water: A Whole New World of Wellness - Saba Yussouf : 1080 · Aug 2023

    0 votes

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38. —
    Sam Qurashi

    Triggered Much? How to Avoid Extremes and Find Your Middle Ground – Sam Qurashi with Dave Asprey : 786 · Jan 2021

    0 votes

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39. —
    Samuel Veissière

    Why You Have CCE (Corona Cognitive Epidemic) and What To Do About It – Samuel Veissière, Ph.D. : 674 · Mar 2020

    0 votes

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40. —
    Sandra Kaufmann

    2025 Biohacking State of the Union: Master Supplementation Guide with Dr. Sandra Kaufmann : 1243 · Jan 2025

    0 votes

    Never again