The Human Upgrade

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio , he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

Website

Every guest on The Human Upgrade

842 guests, ranked by how many people never want them back.

1. —
   Sarah Rahal

   Introducing a REAL Superfood: Using Colostrum for Strong Barriers – Sarah Rahal, MD : 1100 · Oct 2023

   0 votes

   Never again
2. —
   Saundra Dalton-Smith

   3 Rs to Up Your Energy: Rest, Recovery & Restoration – Dr. Saundra Dalton-Smith & Kate Northrup – #851 : 851 · 2 episodes

   0 votes

   Never again
3. —
   Scott Carney

   Stop Fighting Your Environment & Hack Your Homeostasis – Scott Carney : 596 · May 2019

   0 votes

   Never again
4. —
   Scott Nelson

   Shine a (Red) Light on Your Health – Scott Nelson : 639 · Oct 2019

   0 votes

   Never again
5. —
   Sean Berman

   Stem Cell Therapy and Personal Stem Cell Banking with Sean Berman and Kevin Ferber : 1058 · Jun 2023

   0 votes

   Never again
6. —
   Sean Croxton

   #2: The Dark Side of Fat Loss With Sean Croxton · Aug 2011

   0 votes

   Never again
7. —
   Sean O’Mara

   The Truth About Visceral Fat vs Subcutaneous Fat | Dr. Sean O’Mara : 1505 · Jul 2026

   0 votes

   Never again
8. —
   Sean Plotkin

   Hacking Your Biohacks for Better Sleep, Fitness & Weight Control – Interventions With Dave – Sean Plotkin : 939 · May 2022

   0 votes

   Never again
9. —
   Shaahin Cheyene

   Making Billions: Lessons Learned From the King of the Thrill Pill Cult – Shaahin Cheyene · 2 episodes

   0 votes

   Never again
10. —
    Shalin Shah

    Why Oral Testosterone Is the Ultimate Upgrade for Energy, Mood and Longevity (Men AND Women) | Shalin Shah : 1279 · May 2025

    0 votes

    Never again
11. —
    Shaman Durek

    Build Your Spiritual Immunity – Shaman Durek : 633 · 3 episodes

    0 votes

    Never again
12. —
    Shaman Jorge Hachumak

    Ancient Healing Arts for Your Modern Life – Shaman Jorge Hachumak : 968 · Aug 2022

    0 votes

    Never again
13. —
    Shana Alverson

    #110 CrossFit Master Shana Alverson Makes Strong The New Skinny · Apr 2014

    0 votes

    Never again
14. —
    Sid Baker

    Sid Baker: Beetlejuice! Beetlejuice! Beetle Larvae? - #311 · May 2016

    0 votes

    Never again
15. —
    Siggi Clavien

    Here’s How to Get the ULTIMATE Liver (And Why It Will Change Your Life!) Siggi Clavien : 1232 · Dec 2024

    0 votes

    Never again
16. —
    Siim Land

    Stress Takes More Than it Gives: Ways to Adapt and Get Stronger – Siim Land with Dave Asprey : 724 · 2 episodes

    0 votes

    Never again
17. —
    Somi Javaid

    SEXUAL ENERGY SERIES-5: New Options for Women’s Sex Lives – Dr. Somi Javaid : 791 · Feb 2021

    0 votes

    Never again
18. —
    Sophia Kogan

    Menopause, Stress and Female Hair Loss – Dr. Sophia Kogan with Dave Asprey : 793 · 3 episodes

    0 votes

    Never again
19. —
    Srini Pillay

    Focus on Being Unfocused and Train Your Brain For Success - Srini Pillay : 454 · Dec 2017

    0 votes

    Never again
20. —
    Stella Grizont

    How to Fall in Love With Your Work - Stella Grizont : 563 · 3 episodes

    0 votes

    Never again
21. —
    Steve Revelli

    Particle Size Matters: Masterclass in Using Silver for Biohacking - Steve Revelli : 1071 · Jul 2023

    0 votes

    Never again
22. —
    Steve Wood

    Steve Wood: Reduce High Blood Pressure & The Benefits of Isometric Exercise - #234 · Jul 2015

    0 votes

    Never again
23. —
    Steven Breitbach

    Steven Breitbach & Maryam Henein: Honey, We Shrank the Bees - #316 · Jun 2016

    0 votes

    Never again
24. —
    Steven Fowkes

    Increase Your IQ & Your Lifespan For A Dime A Day | Steven Fowkes, Biohacker : 456 · 3 episodes

    0 votes

    Never again
25. —
    Steven Herz

    Embrace Criticism and Don't Take Yes for An Answer – Steven Herz with Dave Asprey : 745 · Oct 2020

    0 votes

    Never again
26. —
    Steven Masley

    Vegetables, Coffee, & The Recipe To Make Alzheimer's Optional - Dr. Steven Masley #447 : 447 · Dec 2017

    0 votes

    Never again
27. —
    Stew Friedman

    Stew Friedman: Success, Leadership, & Less Work - #196 · 2 episodes

    0 votes

    Never again
28. —
    Stewart Friedman

    Parenting Through the New Norm: Tips for Connecting with Your Kids During Stressful Times – Dr. Stewart Friedman : 685 · Apr 2020

    0 votes

    Never again
29. —
    Subir Chowdhury

    The Most Powerful Business Success Strategies That Make All the Difference – Subir Chowdhury - #419 · Jul 2017

    0 votes

    Never again
30. —
    Summer Bock

    Summer Bock: Can Fermented Foods Restore Your Gut? - #251 · Oct 2015

    0 votes

    Never again
31. —
    Susanna Soeberg

    How to Stack Cold Water, Sauna and Breathing to Accelerate Your Metabolism – Susanna Soeberg, Ph.D. : 1014 · Jan 2023

    0 votes

    Never again
32. —
    Susanne Bennett

    #103 Dr. Susanne Bennett Uncovers Upgraded Skin Care · Mar 2014

    0 votes

    Never again
33. —
    Suzanne Gilberg-Lenz

    Menopause Bootcamp: Ditch the BS and Get to Solutions – Dr. Suzanne Gilberg-Lenz : 988 · Oct 2022

    0 votes

    Never again
34. —
    Suzanne Somers

    Suzanne Somers: Toxic Mold, Breast Cancer & C-section Risks - #246 · Sep 2015

    0 votes

    Never again
35. —
    Suzy Batiz

    Inner Programming Hacks from the Queen of Poo – Suzy Batiz with Dave Asprey : 711 · Jun 2020

    0 votes

    Never again
36. —
    Sébastien Page

    The $500 Billion Secret: Why Top Leaders Chase Stress | Sébastien Page : 1272 · Apr 2025

    0 votes

    Never again
37. —
    T.S. Wiley

    HORMONES: How to Balance & Manage Yours - A Top 10 Episode with T.S. Wiley · 2 episodes

    0 votes

    Never again
38. —
    Tami Meraglia

    His & Hers Hormones with Dr. Tami Meraglia · Jun 2016

    0 votes

    Never again
39. —
    Tami Mergalia

    Dr. Tami Mergalia: Testosterone Supplementation, Skinny Fat, & Adrenal Fatigue - #206 · Mar 2015

    0 votes

    Never again
40. —
    Tarique Perera

    Dr. Tarique Perera: Precise Treatment with Transcranial Magnetic Stimulation (TMS) - #242 · Aug 2015

    0 votes

    Never again