The Human Upgrade

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio , he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

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Every guest on The Human Upgrade

842 guests, ranked by how many people never want them back.

1. —
   Adam Bornstein

   #57 Becoming Alpha, Dispelling Myths & Making Changes, with Adam Bornstein · Aug 2013

   0 votes

   Never again
2. —
   Adam Gavine

   Reverse Tissue Aging: The Power of Wasabi Method - Adam Gavine : 1173 · Jun 2024

   0 votes

   Never again
3. —
   Adam Kosloff

   Podcast #7: Low-Carb Diets with Adam Kosloff · Oct 2011

   0 votes

   Never again
4. —
   Adeel Khan

   How I Took 9 Years off My Age: Live From Toronto with Gene Therapy Pioneer Dr. Adeel Khan : 1098 · Oct 2023

   0 votes

   Never again
5. —
   Aggie Lal

   Biohack Like a Woman – Aggie Lal : 1126 · Jan 2024

   0 votes

   Never again
6. —
   Aiden Goggins

   Power Up Your Food With Plants - Aiden Goggins & Glen Matten : 460 · Jan 2018

   0 votes

   Never again
7. —
   Akshay Nanavati

   60 Days Alone in Antarctica: Amputation, Frostbite, and Lessons from Extreme Suffering | Akshay Nanavati : 1286 · 2 episodes

   0 votes

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8. —
   Alan Cash

   Alan Cash: Upgraded Aging & Living Longer with Oxaloacetate – #183 · Dec 2014

   0 votes

   Never again
9. —
   Alan Christianson

   #72 An Idiot’s Guide to Thyroid Health with Dr. Alan Christianson · Nov 2013

   0 votes

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10. —
    Alan Graves

    Biohacking in Space: Prioritizing Prevention to Live Forever - Alan Graves : 1081 · Aug 2023

    0 votes

    Never again
11. —
    Alexander Wunsch

    Alexander Wunsch: Light Medicine, Photobiology and Vitamin D - #277 · Jan 2016

    0 votes

    Never again
12. —
    Alexandra Fine

    Innovative Sex Toys Help Close the Pleasure Gap – Alexandra Fine with Dave Asprey : 809 · Mar 2021

    0 votes

    Never again
13. —
    Allen Meglin

    Mini Episode: Enhance Stem Cell Activation Through Hyperbarics - Dr. Allen Meglin : 1163 · May 2024

    0 votes

    Never again
14. —
    Allie Rae

    WetSpace, Crypto & Taking on Big Tech – Allie Rae : 931 · Apr 2022

    0 votes

    Never again
15. —
    Ally Perlina
    0 votes

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16. —
    Alon Braun

    4 Dimensions All Entrepreneurs Must Master – Alon Braun with Dave Asprey, Part 2 : 842 · 2 episodes

    0 votes

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17. —
    Aly Cohen

    The Deadliest Room in Your House — And How to Detox It for Better Health | Aly Cohen MD : 1278 · May 2025

    0 votes

    Never again
18. —
    Amanda Allen

    #105 Flow State and being a Crossfit Champion with Amanda Allen · Mar 2014

    0 votes

    Never again
19. —
    Amitay Eshel

    The Anti-Aging Skincare Trends That Are DAMAGING Your Skin | Amitay Eshel : 1292 · Jun 2025

    0 votes

    Never again
20. —
    Amy B. Killen
    0 votes

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21. —
    Amy Killen

    Treating & Curing Erectile Dysfunction With Stem Cell Therapy – Dr. Amy Killen #407 · May 2017

    0 votes

    Never again
22. —
    Amy Morin

    Mental Strength Hacks for Everyone – Amy Morin : 579 · Mar 2019

    0 votes

    Never again
23. —
    Amy Myers

    Winning Against Autoimmune Disease with Functional Medicine - Dr. Amy Myers · Feb 2017

    0 votes

    Never again
24. —
    Amy Robach

    Women, Fasting, Keto & Cancer – Amy Robach with Dave Asprey : 779 · Jan 2021

    0 votes

    Never again
25. —
    Anat Baniel

    The Nine Essential Steps For Peak Brain & Body Performance - Anat Baniel · Mar 2017

    0 votes

    Never again
26. —
    Andrea Bemis

    Let Them Eat Dirt: Biohacking Family Nutrition - Andrea Bemis : 1070 · Jul 2023

    0 votes

    Never again
27. —
    Andrea Kuszewski

    #74 Learning Should Not Be Easy with Andrea Kuszewski · Nov 2013

    0 votes

    Never again
28. —
    Andrew Herr

    The Future of Upgrading Humans and the Military - Andrew Herr : 540 · Nov 2018

    0 votes

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29. —
    Andrew Hessel

    Controlling Genetic Destiny with Synthetic Biology, Part 1 – Andrew Hessel : 913 · 2 episodes

    0 votes

    Never again
30. —
    Andrew Heyman

    It's Not Lyme, It's Mold - Dr. Andrew Heyman : 557 · Jan 2019

    0 votes

    Never again
31. —
    Andrew Miller

    Inflammation is Aging Your Brain – Dr. Andrew Miller : 643 · Nov 2019

    0 votes

    Never again
32. —
    Andrew Tilin

    Podcast #18: The Doper Next Door with Andrew Tilin · Feb 2012

    0 votes

    Never again
33. —
    Andy Hnilo

    Skincare Hacks With Meteoric Results – Andy Hnilo : 995 · 4 episodes

    0 votes

    Never again
34. —
    Anese Cavanaugh

    Anese Cavanaugh: Intention, Energy & Presence - #301 · 2 episodes

    0 votes

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35. —
    Ankur Jain

    It’s Time for Us to Disrupt and Rebuild – Ankur Jain : 613 · Jul 2019

    0 votes

    Never again
36. —
    Ann Louise Gittleman

    7 Rules to Reverse Aging and Live Longer – Ann Louise Gittleman with Dave Asprey : 840 · Jul 2021

    0 votes

    Never again
37. —
    Anna Akbari

    #92 Creating Digital Happiness with Anna Akbari – Podcast · Jan 2014

    0 votes

    Never again
38. —
    Anna Cabeca

    Oxytocin: How To Naturally Induce Your MIRACLE Hormone | Anna Cabeca : 1493 · 3 episodes

    0 votes

    Never again
39. —
    Anndrea Hermann

    Hacking Hemp with Anndrea Hermann – Podcast #147 · Aug 2014

    0 votes

    Never again
40. —
    Anousheh Ansari

    Space Ambassador and Business Woman: Anousheh Ansari : 529 · Sep 2018

    0 votes

    Never again