The Human Upgrade

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio , he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

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Every guest on The Human Upgrade

842 guests, ranked by how many people never want them back.

1. —
   Florence Williams

   Biohacking Heartbreak: How to Move on Faster – Florence Williams : 1154 · Apr 2024

   0 votes

   Never again
2. —
   Frank Lipman

   How to Break Away from Western Medicine: Frank Lipman : 519 · Aug 2018

   0 votes

   Never again
3. —
   Gabrielle Reece

   Scream Cream and Weekly Injections (Double Episode) | Gabby Reece : 1521 · Aug 2026

   0 votes

   Never again
4. —
   Geoffrey Woo

   Military Tech Goes Public: Think 30% Faster with This Brain Hack | Geoffrey Woo : 1282 · May 2025

   0 votes

   Never again
5. —
   Gunnar Lovelace

   Taking on the USDA One Penny at a Time with Gunnar Lovelace · Jul 2016

   0 votes

   Never again
6. —
   Ingrid Fetell Lee

   How 10 Elements of Joy Improve Your Outlook and Performance – Legacy Upgrade ft. Ingrid Fetell Lee : 1040 · 2 episodes

   0 votes

   Never again
7. —
   Ivor Cummins

   Reclaim Your Health Freedom: Understanding the Systems Keeping Us Sick - Ivor Cummins : 1085 · Sep 2023

   0 votes

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8. —
   Jack Canfield

   BONUS: Take This Step to Create the Best Year of Your Life – Jack Canfield with Dave Asprey : 774 · 3 episodes

   0 votes

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9. —
   Jake Ducey

   Jake Ducey: Public Speaking, Travelling & Dropping Out of College - #226 · Jun 2015

   0 votes

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10. —
    Jason Fung

    Jason Fung: 3 Rules to Lose 50 Pounds Without Ever Counting a Calorie : 1453 · 4 episodes

    0 votes

    Never again
11. —
    Jason Silva

    The Future is Now, and it is Awesome - Jason Silva : 476 · 2 episodes

    0 votes

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12. —
    Jason Wachob

    The Secrets to Creating Your Own Happy, Healthy Life - Jason Wachob : 1054 · 2 episodes

    0 votes

    Never again
13. —
    Jeff Krasno

    How to Hack Your Stress and Engineer Your Tears to BOOST Longevity | Jeff Krasno : 1244 · Jan 2025

    0 votes

    Never again
14. —
    Jeff Spencer

    Jeff Spencer: Strategic Coaching, Corner Man & The Champions Blueprint - #213 · Apr 2015

    0 votes

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15. —
    Jennifer Cohen

    Why Gen Z Can’t Handle the Real World (and How We Can Help Them) | Jennifer Cohen : 1266 · Apr 2025

    0 votes

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16. —
    Jessica Richman

    Podcast #36:Hacking your Biome with uBiome's Jessica Richman · Jan 2013

    0 votes

    Never again
17. —
    Jessie Inchauspé

    Beat Sugar: The Glucose Goddess Method – Jessie Inchauspé : 1137 · Feb 2024

    0 votes

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18. —
    Jill Bolte Taylor

    New Science Finds Thinking and Feeling in Both Sides of Your Brain – Dr. Jill Bolte Taylor with Dave Asprey : 828 · Jun 2021

    0 votes

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19. —
    Joe De Sena

    Ways to Build a Resilient Family – Joe De Sena : 893 · 2 episodes

    0 votes

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20. —
    Joel Kahn

    Dr. Joel Kahn: Heart Health, Mitochondria, & the Gut - #193 · Feb 2015

    0 votes

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21. —
    John Mackey

    The Whole Foods Diet: Why Eating Real, Plant-Based Foods Can Boost Health & Longevity: John Mackey – #409 · May 2017

    0 votes

    Never again
22. —
    Jonathan Fields

    Discover Your ‘Sparketype’ and Meet Your True Self – Jonathan Fields : 872 · Oct 2021

    0 votes

    Never again
23. —
    Jordan Harbinger

    Jordan Harbinger: Fight-or-Flight, Two Kidnappings, and the Wallet Ruining Your Spine : 1499 · 4 episodes

    0 votes

    Never again
24. —
    Kari Nadeau

    New Solutions for the Growing Food Allergy Epidemic – Dr. Kari Nadeau with Dave Asprey : 768 · Dec 2020

    0 votes

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25. —
    Laila Ali

    How To Build Your Confidence and Fully Commit To Your Life – Laila Ali with Dave Asprey : 831 · Jun 2021

    0 votes

    Never again
26. —
    Light Watkins

    Why Meditation is Your Ultimate Life Hack – Light Watkins and Emily Fletcher : 836 · 2 episodes

    0 votes

    Never again
27. —
    Lisa Mosconi

    Women, Menopause and Alzheimer’s: XX Brain Connections with Lisa Mosconi, Ph.D. : 675 · Mar 2020

    0 votes

    Never again
28. —
    Marc Goodman

    Marc Goodman: Cyber Security, Transhumanism, & Future Crimes - #203 · Mar 2015

    0 votes

    Never again
29. —
    Marie Forleo

    Everything is Figureoutable – Marie Forleo : 625 · Sep 2019

    0 votes

    Never again
30. —
    Marisa Peer

    Why Lying to Yourself Could be a Good Thing – Marisa Peer : 892 · Jan 2022

    0 votes

    Never again
31. —
    Mark Nepo

    Falling Down & Getting Up: Exploring the Path to Resilience – Mark Nepo : 1107 · Nov 2023

    0 votes

    Never again
32. —
    Mark Sisson

    Mark Sisson: The Japanese Walking Hack That Outperforms 10,000 Steps A Day : 1287 · 3 episodes

    0 votes

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33. —
    Matt Kaeberlein

    How Dogs Are Going to Make You Live Longer: Rapamycin & Longevity – Matt Kaeberlein : 1145 · Mar 2024

    0 votes

    Never again
34. —
    Michael Breus

    Lions, Dolphins and Bears, Oh My! With Michael Breus · Sep 2016

    0 votes

    Never again
35. —
    Morgan Spurlock

    On Super Sizing, Terrible Toxins and Being an Inside Man - Morgan Spurlock - #411 · Jun 2017

    0 votes

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36. —
    Naveen Jain

    Why is your Oral Health KILLING you, and what can you do about it?! Naveen Jain : 1228 · 10 episodes

    0 votes

    Never again
37. —
    Neil Pasricha

    Resilience Rising with Neil Pasricha : 679 · Mar 2020

    0 votes

    Never again
38. —
    Nicole LePera

    How to Do the Work, Meet Your Self and Be Your Most Authentic – Nicole LePera, Ph.D. : 1002 · Dec 2022

    0 votes

    Never again
39. —
    Ozan Varol

    How Discovering Your Own Genius & Creativity Will Unlock Your Full Potential – Ozan Varol : 1039 · 2 episodes

    0 votes

    Never again
40. —
    Patrick McKeown

    Breathing Upgrade: Get It Right & Catch Some Serious Air – Patrick McKeown & James Nestor : 945 · 3 episodes

    0 votes

    Never again